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[Neurologic disorders in myeloma disease]
Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952)
|January 1, 1986
Summary
Multiple myeloma frequently causes neurological disorders due to toxic-circulatory issues and mechanical spinal cord compression. Early medical intervention is crucial for managing these myeloma-related neurological complications.
Area of Science:
- Neurology
- Oncology
- Pathophysiology
Context:
- Multiple myeloma is a hematologic malignancy affecting plasma cells.
- Neurological complications are common in multiple myeloma patients.
- Existing diagnostic methods for neurological disorders in myeloma are varied.
Purpose:
- To comprehensively examine neurological disorders in multiple myeloma patients.
- To investigate the pathogenesis of neurological disturbances in myeloma.
- To highlight the necessity of medicated correction for neurological issues.
Summary:
- A study of 120 myeloma patients utilized electroencephalography (EEG), rheoencephalography (REG), electromyography, and neurohistology.
- Neurological disorders, including encephalopathy and neuropathic syndromes, were present in 91.7% of patients.
- Pathogenesis involves toxico-dyscirculatory issues from plasmatic cell infiltration, dysproteinosis, kidney failure, and vertebral column deformation impacting the spinal cord.
Impact:
- Identifies a high prevalence of neurological disorders in multiple myeloma.
- Elucidates the primary pathogenic mechanisms behind these neurological complications.
- Underscores the critical need for timely and effective medical treatment for neurological disturbances in myeloma patients.
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