[ULCER DAMAGE TO THE GASTROINTESTINAL PATH ASSOCIATED WITH HYPERTENSION AS A MANIFESTATION OF COMORBIDITY AMONG...

Area of Science:

• Occupational health
• Gastroenterology
• Cardiology

Background:

• Work-related diseases pose significant health risks to employees in demanding occupations.
• Locomotive brigade workers face occupational hazards that may contribute to chronic health conditions.

Purpose of the Study:

• To investigate clinical and laboratory markers associated with gastrointestinal ulcerative lesions and hypertension.
• To understand the pathogenetic links between these conditions and occupational factors in locomotive workers.
• To identify potential predictors for these work-related diseases.

Main Methods:

• Examined 192 railway workers.
• Assessed general clinical and biochemical blood serum parameters.

Main Results:

• Identified abnormalities in vascular endothelium and signs of systemic inflammation.
• These changes were observed in workers with co-occurring duodenal/gastric ulcers and hypertension.
• Findings suggest a link between occupational hazards and these health issues.

Conclusions:

• Specific clinical and laboratory parameters can serve as early predictors.
• These markers may indicate the comorbid development of ulcers and hypertension.
• The study supports the classification of these conditions as work-related diseases in this cohort.