Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cadherins in Tissue Organization

Cadherins in Tissue Organization

The cadherins are a superfamily of cell adhesion molecules comprising over 180 variants, with specific tissues expressing a particular combination of cadherin types. Cadherins generally exhibit homophilic binding; i.e., cadherins on one cell bind to cadherins of the same or closely related type on another cell. Thus, cells of the same type have a specific affinity to bind to each other and sort themselves into clusters to form tissues.
Cell Sorting During Development
Cell sorting plays an...

Peptide Bonds

Peptide Bonds

A peptide bond covalently attaches amino acids through a dehydration reaction. One amino acid's carboxyl group and another amino acid's amino group combine, releasing a water molecule. The resulting bond is the peptide bond. The products that such linkages form are peptides. As more amino acids join this growing chain, the resulting chain is a polypeptide. Each polypeptide has a free amino group at one end. This end has the N-terminal, or the amino-terminal, and the other end has a free...

Accessory Organs

Accessory Organs

Accessory organs are those that participate in the digestion of food but do not come into direct contact with it like the mouth, stomach, or intestine do. Accessory organs secrete enzymes into the digestive tract to facilitate the breakdown of food.

Protein Organization

Protein Organization

Levels of Organization

Levels of Organization

Biological organization is the classification of biological structures, ranging from atoms at the bottom of the hierarchy to the Earth's biosphere. Each level of the hierarchy represents an increase in complexity that builds upon the previous level.
Molecules Are Composed of Atoms, and Biomolecules Are Assembled from Molecules:
The most basic levels include atoms, molecules, and biomolecules. Atoms, the smallest unit of ordinary matter, are composed of a nucleus and electrons. Molecules...

Organic Compounds

Organic Compounds

All living things are formed mostly of carbon compounds called organic compounds. The category of organic compounds includes both natural and synthetic compounds that contain carbon. Although a single, precise definition has yet to be identified by the chemistry community, most agree that a defining trait of organic molecules is the presence of carbon as the principal element, bonded to hydrogen and other carbon atoms. However, some carbon-containing compounds such as carbonates, cyanides, and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Analytical challenges in mapping the subcellular metabolome and lipidome.

The Analyst·2026

Same author

Reshaping Ru polypyridyl photochemistry with choline-geranate (CAGE) ionic liquids.

Chemical communications (Cambridge, England)·2026

Same author

Targeting NAD Homeostasis: Compartmentalization, Quantification, and Modulation.

Metabolites·2026

Same author

Tunable soy protein isolate hydrogel for nanoparticles brain release.

Journal of materials science. Materials in medicine·2026

Same author

Cerebrospinal fluid CEFA composition is enriched in saturated fatty acids and it is altered in Alzheimer's disease.

Journal of lipid research·2026

Same author

Hepatitis C virus and hepatitis B virus in indolent lymphomas: Prospective data from the international observational NF10 study.

British journal of haematology·2026

Search research articles

Related Experiment Video

Updated: Feb 4, 2026

Screening and Identification of Small Peptides Targeting Fibroblast Growth Factor Receptor2 using a Phage Display Peptide Library

Screening and Identification of Small Peptides Targeting Fibroblast Growth Factor Receptor2 using a Phage Display Peptide Library

Published on: September 30, 2019

Phage-displayed peptides targeting specific tissues and organs.

Josu Andrieu¹, Francesca Re², Laura Russo¹

¹a Department of Biotechnology and Biosciences , University of Milano-Bicocca , Milan , Italy.

Journal of Drug Targeting

|October 4, 2018

Summary

Phage display identifies peptide ligands for various materials. This review compiles peptides targeting specific tissues, aiding biomedical research and preventing redundant findings.

Keywords:

Phage display drug delivery targeting peptides

More Related Videos

Peptides from Phage Display Library Modulate Gene Expression in Mesenchymal Cells and Potentiate Osteogenesis in Unicortical Bone Defects

Peptides from Phage Display Library Modulate Gene Expression in Mesenchymal Cells and Potentiate Osteogenesis in Unicortical Bone Defects

Published on: December 10, 2010

Scalable High Throughput Selection From Phage-displayed Synthetic Antibody Libraries

Scalable High Throughput Selection From Phage-displayed Synthetic Antibody Libraries

Published on: January 17, 2015

Related Experiment Videos

Last Updated: Feb 4, 2026

Screening and Identification of Small Peptides Targeting Fibroblast Growth Factor Receptor2 using a Phage Display Peptide Library

Screening and Identification of Small Peptides Targeting Fibroblast Growth Factor Receptor2 using a Phage Display Peptide Library

Published on: September 30, 2019

Peptides from Phage Display Library Modulate Gene Expression in Mesenchymal Cells and Potentiate Osteogenesis in Unicortical Bone Defects

Peptides from Phage Display Library Modulate Gene Expression in Mesenchymal Cells and Potentiate Osteogenesis in Unicortical Bone Defects

Published on: December 10, 2010

Scalable High Throughput Selection From Phage-displayed Synthetic Antibody Libraries

Scalable High Throughput Selection From Phage-displayed Synthetic Antibody Libraries

Published on: January 17, 2015

Area of Science:

Biotechnology
Molecular Biology
Biomedical Sciences

Background:

Phage display is a key technique for discovering peptide ligands.
Numerous peptide sequences targeting diverse materials have been identified.
Peptides with tissue-targeting capabilities are crucial in biomedical research.

Purpose of the Study:

To create an updated, comprehensive list of phage-displayed peptides targeting specific tissues and organs.
To address the challenge of tracking numerous identified ligands and avoid redundant discoveries.
To analyze the limitations and future prospects of phage display technology.

Main Methods:

Literature review and compilation of existing data on phage-displayed peptides.
Systematic analysis of published studies identifying tissue-specific peptide ligands.
Critical evaluation of the phage display technique's strengths and weaknesses.

Main Results:

A curated list of phage-displayed peptides with demonstrated tissue and organ targeting capabilities.
Identification of frequently targeted tissues and recurring peptide motifs.
Highlighting of potential false positives and under-recognized ligands in the field.

Conclusions:

Phage display remains a valuable tool for identifying targeted peptides in biomedical applications.
An updated compilation is essential for efficient research and development.
Further analysis of limitations and future directions will refine the technique's utility.