Management of Wheezy Preschoolers in the Emergency Department: A Discrete Choice Experiment
Related Experiment Video
Updated: Feb 4, 2026

Choice and No-Choice Bioassays to Study the Pupation Preference and Emergence Success of Ectropis grisescens
Published on: October 30, 2018
Gillian Currie, Jennifer Crotts1, Alberto Nettel-Aguirre
1From the Departments of Paediatrics.
Insights
Pediatric emergency physicians show varied treatment choices for wheezing preschoolers, indicating clinical equipoise on corticosteroid use. Many physicians were willing to enroll children in a randomized controlled trial (RCT) for guidance.
Area of Science:
- Pediatric Emergency Medicine
- Respiratory Medicine
- Clinical Trial Design
Background:
- Wheezing is a common presentation in preschool-aged children in emergency departments.
- Current treatment guidelines for wheezing in this age group are not consistently followed by all physicians.
- There is ongoing debate regarding the efficacy of corticosteroids for preschool wheeze.
Purpose of the Study:
- To determine pediatric emergency physicians' treatment preferences for preschool children with wheeze.
- To identify child-specific characteristics influencing these treatment decisions.
- To assess clinical equipoise by evaluating physician willingness to enroll patients in a placebo-controlled trial of corticosteroids.
Main Methods:
- Discrete choice experiments were used to survey Canadian emergency physicians.
- Physicians' treatment choices for wheezing children were elicited for both emergency department (ED) and discharge scenarios.
- Willingness to enroll children in a randomized controlled trial (RCT) was assessed.
Main Results:
- Albuterol was a common treatment choice for most physicians in all scenarios.
- Physician choices regarding oral corticosteroid use varied significantly (12%-81%) based on clinical factors like age and atopy.
- High willingness (73%-86%) to enroll children in an RCT indicated clinical equipoise.
Conclusions:
- Treatment choices for preschool wheeze vary widely among pediatric emergency physicians, suggesting clinical equipoise on corticosteroid effectiveness.
- Observed management practices for albuterol and corticosteroids deviated from established guidelines.
- Physicians' willingness to participate in an RCT suggests a need for clearer management guidance.
Objectives:
This study aimed to elicit pediatric emergency physician's treatment choices for preschool-aged children with wheeze, determine the characteristics of the presenting child that influence treatment choices, and determine whether there is clinical equipoise by eliciting physician willingness to enroll these children in a placebo-controlled trial of corticosteroids.
Methods:
Discrete choice experiments varying the characteristics of the presenting child were designed to elicit Canadian emergency physician's treatment choices, both in the emergency department (ED) and at discharge, for young children presenting with wheeze and their willingness to enroll in a randomized controlled trial (RCT).
Results:
Most physicians chose to treat children with albuterol both in the ED and at discharge for all clinical scenarios. The proportion of physicians who chose to treat children with oral corticosteroids both in the ED and at discharge varied widely (from 12% to 81%) across all scenarios. Physician preference whether preschool children with wheeze should be treated with corticosteroids varied depending on the child's age, history of atopy, and previous and continuous wheeze. Between 73% and 86% of physicians were willing to enroll these children in an RCT indicating clinical equipoise.
Conclusions:
Physician treatment choices varied widely indicating clinical equipoise as to the effectiveness of corticosteroids in this population of patients. Management choices with respect to albuterol and corticosteroids were not consistent with published national and international guidelines. In line with this finding, physician's considerable willingness to enroll these children in an RCT may suggest that they are seeking guidance on how to manage these patients.
More Related Videos
Related Concept Videos
Applications of GIS: Disaster Management and Emergency Response
Emerging Adulthood
Discrete Fourier Transform
Mate Choice
The Stanford Prison Experiment
Discrete-time Fourier transform
One of the notable...

