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Updated: Feb 4, 2026

Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy
Published on: April 11, 2019
Status epilepticus, electroconvulsive therapy and malignant melanoma
Kenneth R Kaufman1, Aviva Olsavsky2
1Departments of Psychiatry,Neurology and Anaesthesiology,UMDNJ-Robert Wood Johnson Medical School,125 Paterson Street Suite #2200,New Brunswick,NJ 08901,USA.
Abstract:
Status epilepticus (SE), both convulsive and nonconvulsive, is a rare adverse effect of electroconvulsive therapy (ECT). This case report describes SE post-ECT associated with central nervous system (CNS) metastatic melanoma and reviews pertinent literature. The authors recommend that when CNS pathology is suspected, pre-ECT neurology consultation, neuroimaging, and EEG all may be indicated. This is especially important for patients with histories of primary cancers, such as melanoma, that metastasise to the brain.
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