Clozapine induced myocarditis: a case report and literature review
Sunday O Okereke1, Wan My Mohd Abdoh1, Bernadette M Murphy1
1Department of Psychiatry,Adelaide and Meath Hospital including the National Children's Hospital,Tallaght,Dublin 24,Ireland.
Abstract:
Clozapine, the drug of choice for treatment resistant schizophrenia, has a range of serious cardiac side-effects. This paper describes a fatal case of myocarditis in a 48 year old man four weeks after starting clozapine. In particular, this case illustrates how incipient the disorder can be and the need for a high level of suspicion. Difficulties in diagnosing clozapine induced myocarditis and ways to minimise its risk are also discussed.
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