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Updated: Feb 4, 2026

A Generalized Method for Determining Free Soluble Phenolic Acid Composition and Antioxidant Capacity of Cereals and Legumes
Published on: June 10, 2022
Effect of Natural Food Antioxidants against LDL and DNA Oxidative Changes
Sotirios Kiokias1, Charalampos Proestos2, Vassilki Oreopoulou3
1REA-Research Executive Agency, B-1049 Brussels, Belgium. Sotirios.KIOKIAS@ec.europa.eu.
Abstract:
Radical oxygen species formed in human tissue cells by many endogenous and exogenous pathways cause extensive oxidative damage which has been linked to various human diseases. This review paper provides an overview of lipid peroxidation and focuses on the free radicals-initiated processes of low-density lipoprotein (LDL) oxidative modification and DNA oxidative damage, which are widely associated with the initiation and development of atherosclerosis and carcinogenesis, respectively. The article subsequently provides an overview of the recent human trials or even in vitro investigations on the potential of natural antioxidant compounds (such as carotenoids; vitamins C and E) to monitor LDL and DNA oxidative changes.
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