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Anesthetic Management in Corpus Callosum Agenesis
Ebru Tarıkçı Kılıç1, Mehmet Erdem Akçay1, Mehmet Salim Akdemir1
1Department of Anesthesiology, Health Sciences University, Ümraniye Training and Research Hospital, Istanbul, Turkey.
Abstract:
Corpus callosum agenesis develops when the band which connects the two hemispheres of the brain does not occur in utero. It is associated with prenatal infections, genetic factors, toxic exposures, metabolic disorders, and chromosome errors. Mostly seen clinical features are macrocephaly, microcephaly, seizures, motor retardation, hypotonia, eye anomalies, and facial dysmorphisms. Here, we report a case of corpus callosum agenesis syndrome undergoing upper endoscopy under deep sedation with dexmedetomidine. The main anesthetic concerns are difficulty in airway, respiratory problems, gastric reflux, and interaction of the seizures therapy with general anesthetics.
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