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Updated: Feb 4, 2026

Non-enzymatic, Serum-free Tissue Culture of Pre-invasive Breast Lesions for Spontaneous Generation of Mammospheres
Published on: November 8, 2014
Histological Characteristics of Breast Lesions in Uyo, Nigeria
Chukwuemeka Charles Nwafor1, Isaac Assam Udo2
1Department of Pathology, University of Uyo, Uyo, Akwa Ibom State, Nigeria.
Background:
The breast is a common site for pathologies which predominantly involves the female breast. While benign diseases are more common, malignancies are of utmost concern for the patient, clinician, and the pathologist.
Aim:
The aim of this study is to audit the clinical and pathological features of patients with breast lumps in a tertiary center in Nigeria.
Materials And Methods:
This is a retrospective observational study of histologically diagnosed breast lumps over a period of 8 years.
Results:
Lumps were common in the 20-39 years age group (>50%), with a mean age of 34.95 years. Females accounted for 759 (98.1%) of cases. In 467 (60.4%) cases, the lumps measured >5 cm and only 175 (22.6%) cases presented to the surgeon within 12 weeks of noticing a breast lump. Ninety-one (11.8%) cases also presented with axillary lymph nodes, breast pain 79 (10.2%), peau d' orange 56 (7.2%), and ulceration 47 (6.1%). Benign breast disease (BBD) occurred in 401 (51.8%) cases and malignant breast diseases (MBD) occurred in 344 (44.3%) of cases.
Conclusion:
BBD and MBD are common among the young in Uyo. Lumps are the primary complaint and late presentation is the norm.
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