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Related Concept Videos

CRISPR/Cas9 Genome Editing01:28

CRISPR/Cas9 Genome Editing

1.9K
The CRISPR-Cas system serves as a bacterial defense mechanism against invading genetic elements such as viruses and plasmids, forming the foundation for its adaptation as a powerful genome-editing tool. Originally discovered in prokaryotes, this system has been repurposed to revolutionize genetic engineering across a wide range of organisms, including plants, animals, and humans. The core component, Cas9, is an endonuclease derived from Streptococcus pyogenes, capable of introducing...
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RNA Editing02:23

RNA Editing

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RNA editing is a post-transcriptional modification where a precursor mRNA (pre-mRNA) nucleotide sequence is changed by base insertion, deletion, or modification. The extent of RNA editing varies from a few hundred bases, in mitochondrial DNA of trypanosomes, to a just single base, in nuclear genes of mammals. Even a single base change in the pre-mRNA can convert a codon for one amino acid into the codon for another amino acid or a stop codon. This type of re-coding can significantly affect the...
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Genomics02:02

Genomics

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

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Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
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Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

9.1K
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
9.1K
Overview of Advanced Functional Groups02:22

Overview of Advanced Functional Groups

30.0K

Functional groups are groups of atoms with specific chemical properties that occur within organic molecules and are sometimes denoted as “R”. Functional groups can “functionalize” a compound by enabling it to adopt different physical and chemical properties.
Types of Advanced Functional Groups
The table below summarizes some of the major functional groups in organic chemistry.
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Related Experiment Video

Updated: Feb 4, 2026

Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits
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Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits

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Genome Editing in Rice: Recent Advances, Challenges, and Future Implications.

Rukmini Mishra1, Raj Kumar Joshi2, Kaijun Zhao1

  • 1National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing, China.

Frontiers in Plant Science
|October 5, 2018
PubMed
Summary

Genome editing technologies like CRISPR/Cas9 offer advanced solutions for rice improvement, addressing yield stagnation and global food security challenges. These tools accelerate crop enhancement for a growing population.

Keywords:
CRISPR/Cas9CRISPR/Cpf1base editorscrop improvementgenome editingricetargeted mutagenesis

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Efficient Genome Editing of Mice by CRISPR Electroporation of Zygotes
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Efficient Genome Editing of Mice by CRISPR Electroporation of Zygotes

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Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
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Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

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Related Experiment Videos

Last Updated: Feb 4, 2026

Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits
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Author Spotlight: Streamlining Rice Breeding with CRISPR/Cas for Obtaining Optimal Phenotypic and Agronomic Traits

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Efficient Genome Editing of Mice by CRISPR Electroporation of Zygotes
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Efficient Genome Editing of Mice by CRISPR Electroporation of Zygotes

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Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
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Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

Published on: May 25, 2018

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Area of Science:

  • Agricultural Science
  • Genomics
  • Plant Biotechnology

Background:

  • Rice is a vital global food source, but yield stagnation threatens food security due to pests, climate change, and environmental issues.
  • A growing global population necessitates increased rice production to meet future demands.
  • Genomic advancements and genome editing technologies are revolutionizing plant science and agriculture.

Purpose of the Study:

  • To review genome editing strategies for rice improvement.
  • To highlight the applications and advancements of CRISPR/Cas9 in rice.
  • To discuss emerging tools like CRISPR/Cpf1 and base editors for crop enhancement.

Main Methods:

  • Focus on CRISPR/Cas9 as a leading genome editing system for rice.
  • Review of site-specific nucleases (SSNs) and their role in genetic manipulation.
  • Exploration of newer technologies such as CRISPR/Cpf1 and base editors.

Main Results:

  • CRISPR/Cas9 is highly efficient and widely adopted for rice genetic improvement.
  • Rice's genomic resources and small genome size facilitate its use in genome editing studies.
  • CRISPR/Cpf1 and base editors show promise as more accurate and efficient tools.

Conclusions:

  • Genome editing technologies are crucial for overcoming rice yield stagnation and ensuring food security.
  • CRISPR/Cas9, CRISPR/Cpf1, and base editors represent significant progress in rice genetic improvement.
  • Future implications of these tools hold great potential for accelerating crop development and addressing global food challenges.