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Updated: Feb 4, 2026

Three-dimensional Alginate-bead Culture of Human Pituitary Adenoma Cells
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Pituitary Adenoma Apoplexy: Review of Personal Series
Riccardo Ricciuti1, Niccolò Nocchi1, Giorgio Arnaldi2
1Division of Neurosurgery, Ospedali Riuniti di Ancona, Italy.
Background:
Pituitary apoplexy is a life-threatening event with unspecific clinical background and no standardized treatment.
Materials And Methods:
The authors retrospectively analyzed seventeen patients affected by pituitary adenoma apoplexy and treated in a 10-year period. Thirteen patients underwent surgery through transsphenoidal route while four patients have been treated conservatively.
Results:
The endoscopic surgical procedure showed a better result in term of complete removal of the tumor while in the "conservative" group less frequent evidence of hormones' deficiency has been registered. Once a residual lesions was observed a strict radiological follow-up is mandatory.
Conclusions:
According to dedicated literature and pre- and post-operative evidence of personal series, the authors try to provide an algorithm that could help in the standardization of the diagnostic and therapeutic pathways in patients with pituitary adenoma apoplexy.
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