Related Experiment Video

Updated: Feb 4, 2026

Embolic Middle Cerebral Artery Occlusion MCAO for Ischemic Stroke with Homologous Blood Clots in Rats
09:11

Embolic Middle Cerebral Artery Occlusion MCAO for Ischemic Stroke with Homologous Blood Clots in Rats

Published on: September 17, 2014

27.8K

Recurrent Embolic Stroke Caused by Large Cavernous Carotid Aneurysm: Stroke Recurrence Prevention with High-Flow

Hideaki Ono1, Tomohiro Inoue2, Akira Iijima3

  • 1Department of Neurosurgery, Fuji Brain Institute and Hospital, Fujinomiya, Japan.

Asian Journal of Neurosurgery
|October 5, 2018
PubMed

Insights

Large cavernous carotid aneurysms can cause embolic stroke. Urgent surgical exclusion with bypass effectively prevented further strokes in a patient with a thrombosing aneurysm.

Area of Science:

  • Neurosurgery
  • Vascular Neurology
  • Cerebrovascular Disease

Background:

  • Intracranial aneurysms are a known cause of embolic stroke.
  • Optimal management for intracranial aneurysms remains individualized due to lack of established treatment strategies.
  • Large or giant cavernous carotid aneurysms with acute enlargement and thrombosis pose a significant risk for recurrent embolic stroke.

Observation:

  • A 79-year-old female patient experienced recurrent embolic strokes despite antiplatelet therapy due to an enlarging and partially thrombosed large cavernous carotid aneurysm.
  • The patient underwent coil embolization of the primitive trigeminal artery and internal carotid artery (ICA) ligation, coupled with a high-flow bypass from the external carotid artery to the middle cerebral artery.

Findings:

  • The intervention successfully thrombosed the aneurysm.
  • This procedure effectively prevented further embolic stroke events in the patient.

Implications:

  • Acute enlargement and thrombosis of large or giant cavernous carotid aneurysms can precipitate repeated embolic strokes.
  • Emergent exclusion of such aneurysms via proximal ICA occlusion and distal revascularization is vital to avert catastrophic embolic events.

Keywords:
Cavernous carotid aneurysmembolic strokehigh-flow bypassproximal occlusionrecurrence

More Related Videos

Modeling Stroke in Mice: Transient Middle Cerebral Artery Occlusion via the External Carotid Artery07:26

Modeling Stroke in Mice: Transient Middle Cerebral Artery Occlusion via the External Carotid Artery

Published on: May 24, 2021

8.3K
Modeling Stroke in Mice - Middle Cerebral Artery Occlusion with the Filament Model06:28

Modeling Stroke in Mice - Middle Cerebral Artery Occlusion with the Filament Model

Published on: January 6, 2011

94.3K

Related Concept Videos

Regulation of Stroke Volume01:27

Regulation of Stroke Volume

The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
5.2K
Cardiac Output and Stroke Volume01:11

Cardiac Output and Stroke Volume

Cardiac output (CO) is an integral aspect of human physiology, reflecting the heart's efficiency and responsiveness to the body's needs. It represents the volume of blood that the left or right ventricle ejects into the aorta or pulmonary trunk each minute. The CO is calculated by multiplying the heart rate (HR)—the number of heartbeats per minute—by the stroke volume (SV)—the amount of blood pumped out with each heartbeat.
In an average resting adult male, the typical cardiac...
4.9K
Cardiac Output II: Effect of Stroke Volume on Cardiac Output01:22

Cardiac Output II: Effect of Stroke Volume on Cardiac Output

Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
3.4K
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
720
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
423
Gene Flow02:39

Gene Flow

Gene flow is the transfer of genes among populations, resulting from either the dispersal of gametes or from the migration of individuals.
37.9K