Positive and balancing selection on SLC18A1 gene associated with psychiatric disorders and human-unique personality

Daiki X Sato1, Masakado Kawata1

  • 1Graduate School of Life Sciences, Tohoku University Sendai 980-8578 Japan.

Evolution Letters
|October 5, 2018
PubMed

Related Concept Videos

Disorder of Water Balance01:29

Disorder of Water Balance

Water balance disorders are medical conditions that occur when there is a deviation from the body's water volume or osmolarity, disrupting normal homeostasis and leading todehydration, hypotonic hydration, hyperhydration, edema, or water intoxication.
Dehydration
Dehydration occurs when the body loses fluids (particularly water).
Causes:
The major causes of dehydration include excessive sweating, fever, vomiting, diarrhea, and diuresis.
Signs and Symptoms:
Symptoms primarily include intense...
2.5K
Factors Influencing Attraction VI: Personality Traits01:23

Factors Influencing Attraction VI: Personality Traits

Personality traits are fundamental in shaping social perception and influencing interpersonal relationships. Certain traits, such as agreeableness and extraversion, contribute positively to social interactions, whereas others, such as narcissism, have complex and often contradictory effects on how individuals are perceived over time.The Role of Agreeableness and ExtraversionAgreeableness and extraversion are associated with higher levels of interpersonal attractiveness and likability.
240
Polygenic Traits01:18

Polygenic Traits

When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...
69.1K
Chromatin Position Affects Gene Expression02:35

Chromatin Position Affects Gene Expression

Chromatin is the massive complex of DNA and proteins packaged inside the nucleus. The complexity of chromatin folding and how it is packaged inside the nucleus greatly influences  access to genetic information. Generally, the nucleus' periphery is considered transcriptionally repressive, while the cell's interior is considered a transcriptionally active area. 
Topologically Associated Domains (TADs)
The 3-dimensional positioning of chromatin in the nucleus influences the...
24.9K
Trait and State Self-Esteem02:08

Trait and State Self-Esteem

The term self-esteem is often used generically, to refer to how people feel about themselves. However, according to research, there are three distinct constructs that should not be used interchangeably (Brown & Marshall, 2006). 
11.5K
Antisocial Personality Disorder01:24

Antisocial Personality Disorder

Antisocial personality disorder is a chronic mental health condition characterized by persistent patterns of disregard for the rights and well-being of others. Individuals with antisocial personality disorder exhibit behaviors that include deceitfulness, impulsivity, irresponsibility, aggression, and a profound lack of empathy. These traits often manifest early in life and persist into adulthood, leading to significant personal, social, and legal consequences.
Behavioral Characteristics and...
765