Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

6.4K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
6.4K
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

5.5K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
5.5K
Health Literacy01:21

Health Literacy

5.4K
Health literacy is an individual's or a community's capacity to comprehend, receive, read, and use relevant healthcare information and services. The World Health Organization (WHO, 2018) defines health literacy as the cognitive and social skills that determine the ability of individuals to gain access to, understand, and use information in ways that promote and maintain good health. As a result, the WHO helps individuals manage long-term health concerns, participate in preventative...
5.4K
Purpose of Health Records I01:11

Purpose of Health Records I

1.8K
The vital purpose of health records is to provide a complete and accurate account of a patient's medical history, including communication, diagnostic and therapeutic orders, care planning, research, and quality review.
Here's a breakdown of how health records serve these purposes:
1.8K
Purpose of Health Records II01:19

Purpose of Health Records II

1.4K
Health records serve various essential purposes in the healthcare system. Here are some key purposes:
1.4K
Concepts of Health and Illness01:29

Concepts of Health and Illness

17.9K
Health is a condition of the body, mind, and spirit where an individual remains free from illness. Similarly, wellness is an active state, including living a lifestyle that promotes physical, mental, and emotional health. Physical health is critical for the overall well-being and can be affected by lifestyle, activity level, diet, and behavior. The highest attainable standard of health is a fundamental and universal human right. Consider Lisa, a fifteen-year-old born with congenital...
17.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A longitudinal imaging study of the effects of type 2 diabetes and microvascular disease on diabetic bone disease.

Bone·2026
Same author

Sustained Improvement in Renal Function with Palopegteriparatide in Adults with Chronic Hypoparathyroidism: 2-Year Results from the Phase 3 PaTHway-Trial.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2026
Same author

Consensus statement on vitamin D role in metabolic health.

Metabolism: clinical and experimental·2025
Same author

Simplified Protocol Conditions for the Gold-Catalyzed Hydrofluorination of Terminal Aliphatic Alkynes.

The Journal of organic chemistry·2025
Same author

FSH and longitudinal changes in bone marrow adipose tissue composition in older adults.

Bone·2025
Same author

Effects of weight-loss interventions on bone health in people living with obesity.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2025

Related Experiment Video

Updated: Feb 4, 2026

Endoscopic Cholesteatoma Surgery
08:47

Endoscopic Cholesteatoma Surgery

Published on: January 19, 2022

13.1K

Bone Health After Bariatric Surgery.

Claudia Gagnon1,2,3,4, Anne L Schafer5,6,7

  • 1Department of Medicine Université Laval Quebec City Canada.

JBMR Plus
|October 5, 2018
PubMed
Summary

Bariatric surgery, particularly Roux-en-Y gastric bypass (RYGB), significantly impacts bone health, increasing fracture risk. Advanced imaging reveals declines in bone mass and detrimental microstructural changes, necessitating further research for improved patient guidelines.

Keywords:
BIOCHEMICAL MARKERS OF BONE TURNOVERBONE QCT/μCTBONE–FAT INTERACTIONSDXAFRACTURE RISK ASSESSMENT

More Related Videos

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
08:41

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials

Published on: August 13, 2019

8.9K
Intraoperative Ultrasound in Spinal Surgery
05:53

Intraoperative Ultrasound in Spinal Surgery

Published on: August 17, 2022

5.4K

Related Experiment Videos

Last Updated: Feb 4, 2026

Endoscopic Cholesteatoma Surgery
08:47

Endoscopic Cholesteatoma Surgery

Published on: January 19, 2022

13.1K
Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
08:41

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials

Published on: August 13, 2019

8.9K
Intraoperative Ultrasound in Spinal Surgery
05:53

Intraoperative Ultrasound in Spinal Surgery

Published on: August 17, 2022

5.4K

Area of Science:

  • Bone and Mineral Metabolism
  • Bariatric Surgery Outcomes
  • Skeletal Health Research

Background:

  • Bariatric surgery promotes weight loss and resolves obesity comorbidities.
  • Emerging evidence links bariatric surgery to adverse skeletal outcomes.
  • Roux-en-Y gastric bypass (RYGB) is well-studied; sleeve gastrectomy (SG) effects are less defined.

Purpose of the Study:

  • To review clinical research on bariatric surgery's impact on skeletal health.
  • To summarize findings on bone mass, microarchitecture, and fracture risk.
  • To explore potential mechanisms underlying surgical effects on bone.

Main Methods:

  • Review of clinical research, focusing on RYGB and other bariatric procedures.
  • Analysis of epidemiologic studies on fracture risk.
  • Inclusion of patient-oriented studies using advanced skeletal imaging (DXA, QCT, HR-pQCT) and bone turnover markers.

Main Results:

  • Increased fracture risk observed after RYGB and biliopancreatic diversion with duodenal switch.
  • Early, dramatic increases in bone turnover markers post-surgery.
  • Pronounced declines in bone mass and detrimental effects on microarchitecture and bone strength at axial and appendicular sites following RYGB.

Conclusions:

  • Bariatric surgery, especially RYGB, adversely affects bone health, leading to reduced bone mass and fragility.
  • Skeletal changes are multifactorial, involving nutritional, mechanical, hormonal, and body composition factors.
  • Clinical guidelines should address bone health, but further research is needed to refine recommendations.