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Postoperative pain after spinal surgery in the paediatric population
Barbara Kościelniak-Merak1, Ilona Batko, Krzysztof Kobylarz
1Department of Clinical Biochemistry, University Children's Hospital, Faculty of Medicine, Jagiellonian University, Cracow, Poland. b.k.koscielniak@gmail.com.
Insights
Laboratory factors like hemoglobin drop and total protein levels can predict severe postoperative pain in children after extensive spine surgery. These findings aid in early identification and management of pain.
Area of Science:
- Pediatric Surgery
- Pain Management
- Clinical Laboratory Science
Background:
- Postoperative pain is a significant complication, particularly after extensive spinal surgeries.
- Identifying predictive factors for severe pain is crucial for effective patient management.
Purpose of the Study:
- To investigate laboratory predictive factors for intensive postoperative pain in children undergoing extensive spine surgery.
- To correlate specific laboratory values with pain intensity post-surgery.
Main Methods:
- Recruited 41 children (median age 13 years) undergoing extensive spine surgery.
- Classified patients into study (pain score ≥5) and control (pain score <5) groups based on pain scales (NRS, VAS, FPS-R).
- Collected pre-, intra-, and post-operative clinical and laboratory data.
Main Results:
- Intensive postoperative pain correlated with a significant drop in hemoglobin and hematocrit levels.
- Higher fluctuations in mean arterial pressure during surgery were associated with increased pain.
- Elevated total protein concentration post-surgery was observed in children with intensive pain.
Conclusions:
- Drop in hemoglobin and hematocrit, mean arterial pressure fluctuations, and total protein levels are potential prognostic factors for early postoperative pain.
- These laboratory markers can aid in predicting and managing severe pain after extensive spine surgery in pediatric patients.
Introduction:
Postoperative pain is a major aftereffect of surgery. Especially severe occurs after extensive operations within the spine. The goal of the study was to investigate the laboratory predictive factors of intensive postoperative pain in children undergoing extensive surgery Patients and methods: We recruited 41 children, age median 13 years (IQR:10-15 years) undergoing extensive spine surgery. The subjects were divided into two groups based on the intensity of postoperative pain measured using the 10-point numerical rating scale (NRS), visual analog scale (VAS) or faces pain scale-revised (FPS-R). Patients with a score of 5 or higher were included in the study group and those with NRS of less than 5 were included in the control group. We collected detailed clinical and laboratory data before, during and after surgery.
Results:
The highest intensity of pain was observed in the first 6 hours after surgery. The postoperative pain was associated with a higher drop in hemoglobin concentration and hematocrit level in peri-operative period (p=0.006 and p=0.019 respectively) as well as higher changes in mean arterial pressure during surgery. Additionally, we found that children with intensive pain had higher total protein concentration after surgery.
Conclusions:
We reported that the drop in hemoglobin and hematocrit level, fluctuation in mean arterial pressure as well as total protein concentration could be useful prognostic factors of early postoperative pain. < p > < /p >.
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