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Routes of Persuasion

Routes of Persuasion

Persuasion is the process of changing our attitude toward something based on some kind of communication. Much of the persuasion we experience comes from outside forces. How do people convince others to change their attitudes, beliefs, and behaviors? What communications do you receive that attempt to persuade you to change your attitudes, beliefs, and behaviors?

Routes of Drug Administration: Parenteral

Routes of Drug Administration: Parenteral

The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability because the medication bypasses the harsh conditions of the gastrointestinal tract and hepatic metabolism.
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...

Routes of Drug Administration: Overview

Routes of Drug Administration: Overview

Drug administration involves delivering drugs to the body through various routes, such as enteral, parenteral, and topical.
Enteral administration refers to drugs absorbed through the gastrointestinal tract. They can be swallowed (perorally), placed under the tongue (sublingually), or on the inner lining of the cheeks (buccally). Perorally administered drugs take time to be absorbed and have a slower onset of action. The rectal route is another form of enteral administration, which allows for...

Drug Delivery: Enteral Route

Drug Delivery: Enteral Route

The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.

Drug Delivery: Parenteral Route

Drug Delivery: Parenteral Route

The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...

Additional Routes of Drug Administration

Additional Routes of Drug Administration

Choosing the appropriate route of drug administration is significantly influenced by two key factors: the therapeutic objectives and the inherent properties of the drug being used.
Administering drugs via inhalation allows for the direct delivery of gaseous, volatile substances or droplets to different parts of the respiratory tract. One of the advantages of the inhalation route is the rapid absorption of drugs into the circulatory system, which is possible because of the large surface area of...

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Related Experiment Video

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Synthesis of Bimetallic Pt/Sn-based Nanoparticles in Ionic Liquids

Synthesis of Bimetallic Pt/Sn-based Nanoparticles in Ionic Liquids

Published on: August 23, 2018

Hetero-Bimetallic Effect as a Route to Access Multinuclear Complexes.

Zhongrui Chen¹, Gabriel Canard¹, Denis Jacquemin²

¹Aix Marseille Université, CNRS UMR 7325, CINaM , Campus de Luminy, case 913 , 13288 Marseille cedex 09 , France.

Inorganic Chemistry

|October 5, 2018

Summary

Researchers synthesized a novel hetero-bimetallic compound using a quinoid ligand, enabling the creation of a tetranuclear complex (Pd-Ni-Ni-Pd) with unique light-absorbing properties up to the far-red region.

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Area of Science:

Coordination Chemistry
Materials Science
Photophysics

Background:

Development of novel metal complexes with unique electronic and optical properties is crucial.
Exploring hetero-bimetallic compounds offers opportunities for new functionalities.
Ligand design plays a pivotal role in controlling complex structures and properties.

Purpose of the Study:

To synthesize and characterize a novel mononuclear intermediate complex based on a quinoid ligand.
To investigate the formation and properties of a hetero-bimetallic compound derived from the intermediate.
To explore a new strategy for constructing multi-heteronuclear complexes with extended light absorption.

Main Methods:

Synthesis of mononuclear quinoid ligand complex.
Metalation to form hetero-bimetallic compound.
Selective ligand exchange using a bischelating ligand.
Spectroscopic analysis (UV-Vis absorption).
First-principle calculations for electronic structure and excited states.

Main Results:

Successful synthesis of a mononuclear intermediate complex and its hetero-bimetallic derivative.
Observation of an unprecedented hetero-bimetallic effect.
Preparation of a tetranuclear complex (Pd-Ni-Ni-Pd) with absorption extending to the far-red region.
Demonstration of a novel ligand exchange approach using a bischelating ligand for multi-heteronuclear complex synthesis.
Computational insights into ligand exchange mechanisms and electronic excited states.

Conclusions:

A novel synthetic route to multi-heteronuclear complexes has been established.
The developed bischelating ligand exchange method is effective for incorporating planar units.
The resulting tetranuclear complex exhibits significant light-harvesting capabilities in the far-red spectrum.
This work opens new avenues for designing advanced functional materials based on hetero-bimetallic coordination compounds.