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A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
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Multiple sclerosis relapse presenting as an acute cardiomyopathy
Alina D Bayer1, Jonathan F Cahill1, Syed A Rizvi1
1Department of Neurology, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USA.
Multiple Sclerosis and Related Disorders
|October 5, 2018
Summary
Multiple sclerosis is linked to heart problems like Takotsubo cardiomyopathy. This study details two cases where brainstem demyelination from multiple sclerosis triggered this specific heart condition.
Area of Science:
- Neurology
- Cardiology
- Neuroimmunology
Background:
- Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system.
- Cardiovascular dysfunction is an emerging complication of MS.
- Takotsubo cardiomyopathy (TCM) involves acute heart dysfunction without coronary artery disease.
Observation:
- TCM has rarely been associated with brainstem demyelination.
- This report presents two cases of TCM in patients with MS.
- Medullary demyelination secondary to MS was observed in both cases.
Findings:
- The two cases highlight a potential link between MS-related medullary demyelination and TCM.
- This suggests a possible neurological pathway influencing cardiac function in MS patients.
Implications:
- Understanding this association may improve diagnosis and management of cardiovascular complications in MS.
- Further research is warranted to elucidate the pathophysiology connecting MS and TCM.
- This finding could lead to novel therapeutic strategies targeting neuro-cardiac pathways in MS.
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