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Related Concept Videos

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

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Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
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Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

494
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
494
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

545
Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
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Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

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Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
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Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

611
Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
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Cardiomyopathy VI: Nursing Management01:29

Cardiomyopathy VI: Nursing Management

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Assessment: Nursing management of patients with cardiomyopathy begins with a thorough assessment of the patient's history, including a family history of cardiomyopathy or sudden cardiac death, personal history of heart disease, hypertension, diabetes, and any alcohol consumption or drug use.During the physical examination, assess vital signs, look for signs of heart failure (such as edema, jugular venous distention, and cyanosis), auscultate for abnormal heart sounds (like murmurs and gallops),...
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A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
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Multiple sclerosis relapse presenting as an acute cardiomyopathy.

Alina D Bayer1, Jonathan F Cahill1, Syed A Rizvi1

  • 1Department of Neurology, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USA.

Multiple Sclerosis and Related Disorders
|October 5, 2018
PubMed
Summary

Multiple sclerosis is linked to heart problems like Takotsubo cardiomyopathy. This study details two cases where brainstem demyelination from multiple sclerosis triggered this specific heart condition.

Keywords:
Autonomic dysfunctionMedullary demyelinationMultiple sclerosisTakotsubo cardiomyopathy

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Area of Science:

  • Neurology
  • Cardiology
  • Neuroimmunology

Background:

  • Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system.
  • Cardiovascular dysfunction is an emerging complication of MS.
  • Takotsubo cardiomyopathy (TCM) involves acute heart dysfunction without coronary artery disease.

Observation:

  • TCM has rarely been associated with brainstem demyelination.
  • This report presents two cases of TCM in patients with MS.
  • Medullary demyelination secondary to MS was observed in both cases.

Findings:

  • The two cases highlight a potential link between MS-related medullary demyelination and TCM.
  • This suggests a possible neurological pathway influencing cardiac function in MS patients.

Implications:

  • Understanding this association may improve diagnosis and management of cardiovascular complications in MS.
  • Further research is warranted to elucidate the pathophysiology connecting MS and TCM.
  • This finding could lead to novel therapeutic strategies targeting neuro-cardiac pathways in MS.