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Updated: Aug 25, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
Editorial Commentary: Does "No Difference" Really Mean "No Difference"? Not All Anterior Cruciate Ligament
Andrew J Sheean1, Volker Musahl1
1University of Pittsburgh.
Abstract:
Despite the preponderance of biomechanical data suggesting that independent femoral tunnel drilling results in more favorable knee kinematics and superior anterior cruciate ligament footprint restoration when compared with transtibial tunnel drilling, equivalent clinical outcomes associated with both techniques continue to be reported. However, readers could contemplate the meaning of "clinical equivalence" and, perhaps, find themselves wanting better ways to detect differences between surgical techniques.
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