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Effectiveness of Mentha piperita Leaf Extracts against Oral Pathogens: An in vitro Study

Rekha Raghavan1, M P Shyamala Devi2, Megha Varghese2

  • 1Department of Periodontology, Educare Institute of Dental Sciences, Malappuram, Kerala, India, Phone: +919349118552,

The Journal of Contemporary Dental Practice
|October 6, 2018
PubMed
Abstract

Insights

Mentha piperita leaf extract demonstrated significant antimicrobial activity against common oral pathogens like Streptococcus mutans. This natural extract shows promise as an alternative to conventional treatments for oral diseases.

Area of Science:

  • Oral Microbiology
  • Natural Product Chemistry
  • Antimicrobial Agents

Background:

  • Oral diseases are frequently caused by microbial infections.
  • Conventional treatments may have limitations or side effects.
  • Herbal remedies are increasingly explored for therapeutic potential.

Purpose of the Study:

  • To evaluate the antimicrobial efficacy of Mentha piperita leaf extract.
  • To assess its activity against key oral pathogens.
  • To compare its effectiveness with a standard antiseptic.

Main Methods:

  • Mentha piperita leaf extract prepared using cold water extraction.
  • Tested against Streptococcus mutans, Aggregatibacter actinomycetemcomitans, and Candida albicans.
  • Zones of inhibition measured, compared to 0.2% chlorhexidine using ANOVA.

Main Results:

  • Mentha piperita extract exhibited significant antimicrobial activity.
  • Maximum inhibition observed against S. mutans, followed by A. actinomycetemcomitans and C. albicans.
  • Statistical analysis confirmed significant efficacy (p < 0.001) compared to chlorhexidine.

Conclusions:

  • Mentha piperita extract possesses notable antimicrobial properties against oral microorganisms.
  • It can be considered a potential alternative or complementary therapy for oral diseases.
  • Findings provide valuable information for dental professionals regarding herbal medication efficacy.
Keywords:
Antimicrobial activityMentha piperitaOral pathogen Zone of inhibition.

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