A one-dimensional solid-state NMR approach for ¹⁴NH/¹⁴NH overtone correlation through ¹H/¹H mixing under fast MAS

Homonuclear correlations are key to structural studies using solid-state NMR. In this contribution, using 14N overtone transition (OT) as a selective excitation approach, we propose a proton-detected one-dimensional (1D) 14NOT/14NOT/1H correlation solid-state NMR method mediated through 1H/1H mixing at fast magic angle spinning to achieve NH/NH proximities in naturally abundant samples. The proposed method is time efficient by a factor of ∼7.5 in comparison to the existing fundamental 14N frequency-based three-dimensional (3D) 14N/14N/1H correlation method.