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[Effect of ACTH fragments on the aggressive-defensive behavior of the rat]

L A Sever'ianova, D V Plotnikov

Fiziologicheskii Zhurnal SSSR Imeni I. M. Sechenova

|December 1, 1986

Abstract:

ACTH4-10 and ACTH5-10 enhanced the fear response and footshock-induced aggression in male rats (50 and 150 mcg/kg, i.p.). ACTH4-10 seemed to produce the corticotropin (ACTH1-39) neuromodulatory behavioral effect which involved the facilitation of the brain muscarinic receptor activation.

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