Related Experiment Video
Updated: Feb 4, 2026
A Murine Tail Lymphedema Model
Published on: February 10, 2021
A Systematic Review of the Outcomes Used to Assess Upper Body Lymphedema
Robyn Sierla1,2, Elizabeth Sian Dylke3, Sharon Kilbreath4
1a Faculty of Health Sciences , University of Sydney , Sydeny , Australia.
Purpose:
To ascertain how change in upper body lymphedema is assessed and understand how clinically significant change is determined.
Method:
A systematic search of the literature resulted in 55 eligible studies for analysis.
Results:
A range of assessment methods, measurement protocols, and outcomes were used in the literature. Of the 21 studies in which thresholds for change were set a priori, 20 different thresholds were reported.
Conclusion:
How data was measured, analysed and reported was inconsistent across studies. Consensus on a core outcome set with standardised assessment protocols and reporting; and investigation into empirically based minimum important differences (MID) is needed.
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