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Fluoride Intake of Infants from Formula
Insights
Infant formula reconstituted with optimally fluoridated water may increase the risk of dental fluorosis. Careful consideration of water fluoride levels is crucial for young children to prevent excessive fluoride intake.
Area of Science:
- Pediatric Nutrition
- Environmental Health
- Dental Public Health
Background:
- Infant formula is a primary source of nutrition for many infants.
- Water fluoride levels vary geographically, impacting reconstituted formula.
- Dental fluorosis is a concern related to excessive fluoride intake during tooth development.
Purpose of the Study:
- To evaluate fluoride intake in infants consuming formula reconstituted with different water sources.
- To assess the potential risk of dental fluorosis based on fluoride intake levels.
Main Methods:
- Collected data on infant demographics, formula, and water consumption.
- Analyzed fluoride concentrations in reconstituted formula and water.
- Estimated infant fluoride intake and compared it to the recommended upper limit (UL).
Main Results:
- Infants consumed formula with minimally fluoridated water (0.0-0.3 ppm).
- 4.4% of infants exceeded the UL of 0.1mg/kg/day.
- Using optimally fluoridated water (0.7 ppm) predicted 36.8% of infants exceeding the UL.
Conclusions:
- Optimally fluoridated water may elevate fluorosis risk in infants under six months.
- Further research with multi-site, multi-year follow-up is needed to confirm fluorosis incidence.
Objective:
This study aimed to assess fluoride intake in infants from formula reconstituted with water, with fluorosis risk in mind.
Study Design:
Data on water source, formula brand/type, volume of formula consumption and infant weight were collected for infants at two-, four-, six-, nine- and twelve-month pediatrician well child visits. Identified formula brands and water types were reconstituted and analyzed for fluoride concentration. Patient body mass and volume consumed/day were used to estimate fluoride intake from reconstituted formula. Descriptive statistics, one-way analysis of variance and chi-square tests were utilized.
Results:
All infants consumed formula reconstituted with minimally fluoridated water (0.0- 0.3 ppm). 4.4% of infants exceeded the recommended upper limit (UL) of 0.1mg/kg/day. Although mean daily fluoride consumption significantly differed among all groups, the proportion of infants at each visit milestone that exceeded daily fluoride intake of 0.1mg/kg/day was not statistically significantly different (p>0.05) for any age group. Predicted values calculated with optimally fluoridated water (0.7ppm) resulted in 36.8% of infants exceeding the UL.
Conclusions:
Optimally fluoridated water may increase fluorosis risk for patients younger than six months. Future investigation should include multiple sites and multi-year follow-up to assess actual fluorosis incidence.
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