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IMG/M v.5.0: an integrated data management and comparative analysis system for microbial genomes and microbiomes
I-Min A Chen1, Ken Chu1, Krishna Palaniappan1
1Department of Energy, Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA.
Nucleic Acids Research
|October 6, 2018
Summary
The Integrated Microbial Genomes & Microbiomes (IMG/M) system v.5.0 offers enhanced tools for analyzing microbial genomes and metagenomes. This updated database provides expanded data content and improved search functionalities for researchers.
Area of Science:
- Microbiology
- Bioinformatics
- Genomics
Background:
- The Integrated Microbial Genomes & Microbiomes (IMG/M) system is a comprehensive resource for microbial genomics.
- Previous versions have facilitated the analysis of diverse microbial datasets.
Purpose of the Study:
- To introduce the Integrated Microbial Genomes & Microbiomes system version 5.0 (IMG/M v.5.0).
- To highlight new features and data expansion in the latest IMG/M release.
Main Methods:
- Data integration from Joint Genome Institute (JGI), external submissions, and public archives (e.g., NCBI).
- Processing through the IMG annotation pipeline and loading into the IMG data warehouse.
- Utilizing IMG's web interface for comparative analysis of isolate genomes and metagenomes.
Main Results:
- IMG/M v.5.0 includes annotated datasets for archaea, bacteria, eukarya, plasmids, viruses, and various metagenomic data types.
- Data content has increased by 60% since the previous report.
- New features include an enhanced genome search, advanced statistical tools, and support for metagenome binning.
Conclusions:
- IMG/M v.5.0 provides an expanded and more powerful platform for microbial genomics and metagenomics research.
- The system offers open access to public data and a secure environment for private data analysis via the IMG/MER system.
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