Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants01:18

Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants

2.4K
Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
2.4K
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

1.9K
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
1.9K
Characteristics of Practical Op Amps01:16

Characteristics of Practical Op Amps

869
A difference amplifier, a crucial component in numerous electronic devices, ideally amplifies only the difference-mode signal, which is the difference between two input signals. However, in practical circuits, the output voltage depends on both the differential gain and the common-mode gain.
The ratio of differential gain to the common-mode gain is defined as the common-mode rejection ratio (CMRR). This ratio quantifies the ability of operational amplifiers (op-amps) to reject common-mode...
869
Theoretical Foundations of Nursing Practice01:30

Theoretical Foundations of Nursing Practice

17.5K
Theories play an essential role in organizing patient care. Theories refer to a proposed or followed belief, policy, or procedure that is the basis for action. Nursing theories are knowledge-based concepts that guide nurses' actions, influence nursing education and practice, and allow nurses to care for their patients.
Theories provide a perspective to assess patients' conditions and organize data and methods. They also assist in analyzing and interpreting information. They represent a...
17.5K
Equivalent Circuits for Practical Transformers01:28

Equivalent Circuits for Practical Transformers

1.4K
The practical equivalent circuits of single-phase two-winding transformers exhibit significant deviations from their idealized versions due to the inherent properties of winding resistance and finite core permeability. These properties result in real and reactive power losses, affecting the transformer's performance. Understanding these deviations is crucial for designing more efficient transformers.
In a practical transformer, each winding exhibits resistance and leakage reactance. The...
1.4K
Buffer Effectiveness02:19

Buffer Effectiveness

55.3K
Buffer solutions do not have an unlimited capacity to keep the pH relatively constant . Instead, the ability of a buffer solution to resist changes in pH relies on the presence of appreciable amounts of its conjugate weak acid-base pair. When enough strong acid or base is added to substantially lower the concentration of either member of the buffer pair, the buffering action within the solution is compromised.
The buffer capacity is the amount of acid or base that can be added to a given volume...
55.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[INFLAMMATION AND HEMOCOAGULATION].

Klinicheskaia meditsina·2018
Same author

Comparative assessment of the effectiveness of treatment of pulmonary thromboembolism in elderly patients.

Klinicheskaia meditsina·2018
Same author

[Non-vitamin K antagonist oral anticoagulants for heart diseases].

Terapevticheskii arkhiv·2017
Same author

[ANTICOAGULANTS TODAY].

Klinicheskaia meditsina·2016
Same author

[Aleksndr Leonidovich Myasnikov].

Klinicheskaia meditsina·2016
Same author

[ARTERIAL HYPERTENSION: A MODERN VIEW OF THE PROBLEM].

Klinicheskaia meditsina·2015

Related Experiment Video

Updated: Feb 4, 2026

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
11:17

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood

Published on: October 12, 2012

14.4K

[New anticoagulants in clinical practice. Effectiveness and problems].

I N Bokarev, T B Kondrat'eva

    Klinicheskaia Meditsina
    |October 6, 2018
    PubMed
    Summary

    New oral anticoagulants and vitamin K antagonists effectively treat venous issues, atrial fibrillation, and acute coronary syndrome. This analysis reviews their benefits and complication prevention strategies for improved patient outcomes.

    More Related Videos

    Assessment of the Anticoagulant and Anti-inflammatory Properties of Endothelial Cells Using 3D Cell Culture and Non-anticoagulated Whole Blood
    07:08

    Assessment of the Anticoagulant and Anti-inflammatory Properties of Endothelial Cells Using 3D Cell Culture and Non-anticoagulated Whole Blood

    Published on: September 5, 2017

    8.9K
    A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice
    08:55

    A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice

    Published on: April 17, 2019

    18.9K

    Related Experiment Videos

    Last Updated: Feb 4, 2026

    Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
    11:17

    Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood

    Published on: October 12, 2012

    14.4K
    Assessment of the Anticoagulant and Anti-inflammatory Properties of Endothelial Cells Using 3D Cell Culture and Non-anticoagulated Whole Blood
    07:08

    Assessment of the Anticoagulant and Anti-inflammatory Properties of Endothelial Cells Using 3D Cell Culture and Non-anticoagulated Whole Blood

    Published on: September 5, 2017

    8.9K
    A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice
    08:55

    A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice

    Published on: April 17, 2019

    18.9K

    Area of Science:

    • Pharmacology
    • Cardiology
    • Hematology

    Background:

    • Venous thromboembolism, atrial fibrillation, and acute coronary syndrome are significant health concerns.
    • Anticoagulant therapy is crucial for managing these conditions and preventing thrombotic events.
    • Traditional vitamin K antagonists have limitations, necessitating exploration of newer agents.

    Purpose of the Study:

    • To evaluate the efficacy of new oral anticoagulants (NOACs) compared to vitamin K antagonists (VKAs).
    • To identify the advantages of NOACs in treating venous problems, atrial fibrillation, and acute coronary syndrome.
    • To outline methods for preventing complications associated with anticoagulant therapy.

    Main Methods:

    • Comparative analysis of clinical trial data and observational studies.
    • Review of pharmacological profiles and pharmacokinetic properties of NOACs and VKAs.
    • Assessment of bleeding risk and other adverse events.

    Main Results:

    • NOACs demonstrate comparable or superior efficacy to VKAs in preventing thromboembolic events.
    • NOACs offer advantages such as predictable pharmacokinetics and fewer drug-food interactions.
    • Established protocols for complication prevention are vital for safe and effective anticoagulation.

    Conclusions:

    • NOACs represent a significant advancement in anticoagulant therapy for major cardiovascular and venous conditions.
    • Understanding the benefits and risks of different anticoagulants is essential for personalized treatment strategies.
    • Proactive management of potential complications enhances therapeutic outcomes and patient safety.