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Updated: Feb 4, 2026

In Vivo Methods to Assess Retinal Ganglion Cell and Optic Nerve Function and Structure in Large Animals
Published on: February 26, 2022
Retinal nerve fiber layer thickness in optic neuritis with MOG antibodies: A systematic review and meta-analysis
Anjiao Peng1, Masako Kinoshita2, Wanlin Lai1
1Department of Neurology, West China Hospital, Sichuan University, Chengdu, China.
Abstract:
This meta-analysis aimed to systematically review current literature measuring the thickness of retinal nerve fiber layer (RNFL) in patients with myelin oligodendrocyte glycoprotein antibodies (MOG-ab) associated optic neuritis. Ten studies were enrolled and the results showed that the degree of RNFL loss in MOG-ab-positive optic neuritis patients may not differ from that of AQP4-ab patients. However, patients who were positive for MOG-ab showed more severe RNFL loss than those who were seronegative.
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