Only Para-Hydrogen Spectroscopy (OPSY) Revisited: In-Phase Spectra for Chemical Analysis and Imaging
Andrey N Pravdivtsev1, Vitaly P Kozinenko2,3, Jan-Bernd Hövener1
1Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center Schleswig-Holstein (UKSH) , Kiel University , Am Botanischen Garten 18 , 24118 , Kiel , Germany.
Abstract:
We revisited only para-hydrogen spectroscopy (OPSY) for the analysis of para-hydrogen-enhanced NMR spectra at high magnetic fields. We found that the sign of the gradients and interpulse delays are pivotal for the performance of the sequence: the variant of double-quantum filter OPSY, where the second time interval is twice as long as the first one (OPSYd-12) converts the antiphase spectrum to in-phase and efficiently suppresses the background signal in a single scan better than the other variants. OPSYd-12 strongly facilitates the analysis of para-hydrogen-derived NMR spectra in homogeneous and inhomogeneous magnetic fields. Furthermore, the net magnetization produced is essential for subsequent applications such as imaging, e.g., in a reaction chamber or in vivo.
Related Concept Videos
Emission Spectra
Hydrogen Bonds
Hydrogen Bonds Control the World!
Because hydrogen has very weak electronegativity when it binds with a strongly electronegative atom, such as oxygen or nitrogen, electrons in the bond are unequally shared....
Hydrogen Bonds
NMR Spectroscopy: Chemical Shift Overview
For instance, the proton...
Chemical Formulas
Chemical Reactions
Chemical Reactions Rearrange Atoms into New Substances
A chemical reaction takes starting materials—the reactants—and changes them...


