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Apexification: A systematic review.

Fabricio Guerrero1, Asunción Mendoza2, David Ribas2

  • 1Department of Odonto-Stomatology, Faculty of Dentistry, University of Barcelona, Barcelona, Spain.

Journal of Conservative Dentistry : JCD
|October 9, 2018
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Apexification using calcium hydroxide is a proven treatment for immature permanent teeth with pulpal necrosis. This therapy helps improve the prognosis for teeth with underdeveloped roots and thin walls.

Keywords:
Apexificationendodontic treatmentimmature permanent teethpulp regenerationrevascularization

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Area of Science:

  • Dentistry
  • Endodontics
  • Regenerative Dentistry

Background:

  • Pulpal necrosis in immature permanent teeth results in short roots, thin walls, and poor crown-root ratio, compromising tooth survival.
  • Apexification is a key treatment for immature permanent teeth with pulpal pathology, aiming to improve prognosis.

Purpose of the Study:

  • To review clinical investigations on the evolution of apexification treatments for immature permanent teeth with pulpal pathology.
  • To assess the efficacy of calcium hydroxide in apexification procedures.

Main Methods:

  • An electronic literature search was conducted using PubMed, Scopus, and Cochrane databases.
  • The search focused on clinical studies investigating treatments for permanent teeth with open apices and pulpal pathology.

Main Results:

  • Eleven clinical studies on apexification treatments were identified.
  • Calcium hydroxide has been consistently used and validated as an effective apexification therapy over many years.

Conclusions:

  • Apexification, particularly with calcium hydroxide, remains a valid and established treatment for immature permanent teeth requiring root development completion.
  • The reviewed studies support the long-term application of calcium hydroxide in managing pulpal necrosis in immature permanent teeth.