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Updated: Feb 4, 2026

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Detection and Enrichment of Rare Antigen-specific B Cells for Analysis of Phenotype and Function
Published on: February 16, 2017
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A Rare Case of Localized Tetanus.
1Department of Intensive Care Medicine, Shree Krishna Hospital, Karamsad, Anand, Gujarat, India.
Summary
Tetanus, a severe infection from Clostridium tetani, can present rarely. Early recognition and prompt treatment, including wound care and antitoxin, are crucial for managing this potentially fatal disease.
Area of Science:
- Infectious Diseases
- Bacteriology
- Neurology
Background:
- Tetanus is a serious, potentially fatal illness caused by Clostridium tetani.
- Common presentations include generalized and neonatal tetanus, with cephalic and localized tetanus being rare.
Observation:
- A 55-year-old male farmer with a toe injury developed a rare form of tetanus.
- The patient received surgical wound exploration, washout, human tetanus immunoglobulin, tetanus toxoid, and antibiotics.
Findings:
- Early recognition of rare tetanus presentations, like localized tetanus, is vital.
- Prodromal symptoms may precede generalized tetanus, highlighting the need for vigilance.
Implications:
- Prompt diagnosis and management are key to successful tetanus treatment.
- Treatment involves neutralizing toxins, eliminating bacteria, controlling spasms, and supportive care for respiratory and autonomic dysfunction.
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