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Dermatoglyphic Analysis in Parents with Cleft Children: A Comparative Study.

D Jaya Harika1, E Sridevi1, A J Sai Sankar1

  • 1Department of Pedodontics and Preventive Dentistry, Sibar Institute of Dental Sciences, Guntur, Andhra Pradesh, India.

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Summary

Dermatoglyphics variations in parents can predict clefting in offspring. This study analyzed dermatoglyphic patterns in parents of children with and without clefts, identifying potential markers for genetic counseling.

Keywords:
A-b ridge countATD angledermatoglyphicsnonsyndromic cleft lip/palatepattern typestotal ridge count

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Area of Science:

  • Genetics
  • Developmental Biology
  • Forensic Science

Background:

  • Altered dermatoglyphics are observed in children with clefts.
  • Predictive markers in prior generations can aid genetic counseling and preventive strategies for cleft anomalies.

Purpose of the Study:

  • To identify dermatoglyphic variations in parents of children with clefts.
  • To establish dermatoglyphic markers for predicting cleft occurrence in offspring.

Main Methods:

  • Dermatoglyphic prints were collected from 400 parents (25-45 years) in two groups: parents with cleft children (Group A) and parents with healthy children (Group B).
  • Analysis included pattern types, total ridge count (TRC), a-b ridge count, atd angle, and asymmetry.

Main Results:

  • Significant differences in pattern types, TRC, a-b ridge count, and atd angle were found between Group A and Group B.
  • Absence of the t point was noted in mothers of children with clefts.

Conclusions:

  • Dermatoglyphics serve as a valuable tool for studying developmental instability in cleft anomalies.
  • Findings provide data for assessing the genetic etiology of clefting and inform potential predictive measures.