Related Experiment Video
Updated: Feb 4, 2026

Establishing a Diaphyseal Femur Fracture Model in Mice
Published on: December 9, 2022
Submuscular plates versus flexible nails in preadolescent diaphyseal femur fractures
L-K Chen1, B T Sullivan1, P D Sponseller1
1Department of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, Maryland, USA.
Insights
Flexible nails (FNs) offer advantages over submuscular plates (SMPs) for pediatric femur fractures, reducing operative time and blood loss. FNs also led to shorter hospital stays, making them a potentially more efficient treatment option.
Area of Science:
- Orthopedic surgery
- Pediatric trauma
- Biomedical engineering
Background:
- Diaphyseal femur fractures are common in children.
- Submuscular plates (SMPs) and flexible nails (FNs) are surgical options.
- Outcomes of these methods require comparative analysis.
Purpose of the Study:
- To compare patient characteristics, operative time, blood loss, hospital stay, and complications.
- The study focuses on pediatric diaphyseal femur fractures.
- Comparison is between submuscular plates (SMPs) and flexible nails (FNs).
Main Methods:
- Retrospective review of 58 children with diaphyseal femur fractures.
- Treatment groups: 30 with SMPs and 28 with FNs (2005-2017).
- Exclusion criteria: pathological fractures and musculoskeletal comorbidities.
Main Results:
- FNs associated with significantly shorter operative time for insertion and removal compared to SMPs.
- FNs demonstrated less estimated blood loss (EBL) during insertion (p < 0.001).
- The FN group experienced a shorter length of hospital stay (LOS) post-insertion (p = 0.032).
Conclusions:
- Flexible nails (FNs) are associated with reduced operative time and EBL for insertion.
- FNs also correlate with a shorter post-insertion LOS in pediatric diaphyseal femur fractures.
- Both methods had comparable rates of surgical site infections; implant irritation was more common with FNs.
Purpose:
To compare patient characteristics, operative time, estimated blood loss (EBL), postoperative length of hospital stay (LOS) and complications after insertion and removal of submuscular plates (SMPs) versus flexible nails (FNs) for paediatric diaphyseal femur fractures.
Methods:
We reviewed records of 58 children (mean age, 7.7 years SD 2.0) with diaphyseal femur fractures who underwent treatment with SMPs (n = 30) or FNs (n = 28) from 2005 to 2017 (mean follow-up, 22 months SD 28). Patients with pathological fractures or musculoskeletal comorbidities were excluded. Alpha = 0.05.
Results:
Insertion of FNs was associated with shorter operative time (ß = -24 mins) and less EBL (ß = -38 mL) (both, p < 0.001) compared with insertion of SMPs, after adjusting for fracture type and time from beginning of study period. Removal of FNs was also associated with shorter operative time (ß = -15 min) compared with removal of SMPs (p < 0.001). EBL during removal was similar between groups (p = 0.080). The FN group had a shorter LOS after insertion (ß = -0.2 d) compared with the SMP group (p = 0.032). Four patients treated with SMPs and three treated with FNs developed surgical site infections. Two patients treated with SMPs and seven treated with FNs experienced implant irritation that resolved with removal. No other complications occurred.
Conclusion:
Compared with SMPs, FNs were associated with shorter operative time (for insertion and removal), less EBL (for insertion) and shorter post-insertion LOS in patients with diaphyseal femur fractures.
Level Of Evidence:
III.
More Related Videos
04:41Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner
Published on: June 6, 2025
07:41An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
Published on: November 13, 2016
Related Concept Videos
Accessory Structures of the Skin: Nails
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...
Bones of the Lower Limb: Femur and Patella
Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
¹H NMR of Conformationally Flexible Molecules: Temporal Resolution
Column Efficiency: Plate Theory
A higher number of theoretical plates signifies better column efficiency and improved separation capabilities. Plate height affects bandwidth and separation quality; it is inversely...
Electric Field of Parallel Conducting Plates
Consider a cross-section of a thin, infinite conducting plate having a positive charge. For such a large thin plate, as the thickness of the plate tends to zero, the positive charges lie on the plate's two large faces. Without an external electric field, the...