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Updated: Feb 4, 2026

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
Published on: September 25, 2019
Luxury perfusion: A paradoxical finding and pitfall of CT perfusion in subacute infarction of brain
Houman Sotoudeh1, Omid Shafaat2, Aparna Singhal1
1Department of Neuroradiology, University of Alabama at Birmingham (UAB), 619 19th St S, Birmingham, AL 35294, USA.
Abstract:
In the context of recent guidelines for stroke management, application of computed tomographic perfusion (CTP) is anticipated to increase, especially within 6-24 hours after stroke onset. There are commercially available software packages to help to detect the infarct core and the penumbra, however, the results of these software are not always straightforward that might cause incorrect CTP interpretation. We present here a case of acute ischemic stroke in which the CTP software misinterpreted the results by labeling the normal hemisphere as infarction and ischemia due to luxury perfusion of the infarcted hemisphere. Awareness of laterality of the patient's symptoms and the understanding of functioning of perfusion analysis software is necessary to avoid this pitfall.
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