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Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
Published on: November 26, 2018
Blastoschizomyces capitatus pneumonia in a patient with untreated chronic lymphocytic leukemia
Laura Trovato1,2, Maria Domina2, Ada Vancheri3
1U.O.C. Laboratory Analysis Unit, A.O.U. "Policlinico-Vittorio Emanuele", Via S.Sofia 78, Catania 95123, Italy.
Abstract:
Several cases have been reported of B. capitatus infections in immunocompromised patients. Acute leukemia is the main predisposing factor. Chronic lymphocytic leukemia (CLL) is not usually associated with opportunistic infections. We report a case of pulmonary infection by B. capitatus in a patient with untreated chronic lymphocytic leukemia. Although the patient had a complete recovery, we believe that this report will alert clinicians to consider B. capitatus as possible cause of severe pneumonia in untreated CLL.
Insights
Fungal infections by Blastomyces capitatus (B. capitatus) are rare in chronic lymphocytic leukemia (CLL). This case highlights B. capitatus as a potential cause of severe pneumonia in untreated CLL patients.
Area of Science:
- Mycology
- Infectious Diseases
- Hematology
Background:
- Blastomyces capitatus (B. capitatus) infections are typically observed in immunocompromised individuals.
- Acute leukemia is a known predisposing factor for B. capitatus infections.
- Chronic lymphocytic leukemia (CLL) is generally not associated with opportunistic infections.
Observation:
- A case of pulmonary infection caused by B. capitatus in a patient with untreated CLL is presented.
- The patient had no prior history of opportunistic infections.
Findings:
- This report documents a rare instance of B. capitatus pulmonary infection in a patient with untreated CLL.
- The patient achieved a complete recovery from the infection.
Implications:
- Clinicians should consider B. capitatus as a potential cause of severe pneumonia in patients with untreated CLL.
- This case expands the understanding of opportunistic infections in CLL patients.
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