Blastoschizomyces capitatus pneumonia in a patient with untreated chronic lymphocytic leukemia

Laura Trovato1,2, Maria Domina2, Ada Vancheri3

  • 1U.O.C. Laboratory Analysis Unit, A.O.U. "Policlinico-Vittorio Emanuele", Via S.Sofia 78, Catania 95123, Italy.

Insights

Fungal infections by Blastomyces capitatus (B. capitatus) are rare in chronic lymphocytic leukemia (CLL). This case highlights B. capitatus as a potential cause of severe pneumonia in untreated CLL patients.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Hematology

Background:

  • Blastomyces capitatus (B. capitatus) infections are typically observed in immunocompromised individuals.
  • Acute leukemia is a known predisposing factor for B. capitatus infections.
  • Chronic lymphocytic leukemia (CLL) is generally not associated with opportunistic infections.

Observation:

  • A case of pulmonary infection caused by B. capitatus in a patient with untreated CLL is presented.
  • The patient had no prior history of opportunistic infections.

Findings:

  • This report documents a rare instance of B. capitatus pulmonary infection in a patient with untreated CLL.
  • The patient achieved a complete recovery from the infection.

Implications:

  • Clinicians should consider B. capitatus as a potential cause of severe pneumonia in patients with untreated CLL.
  • This case expands the understanding of opportunistic infections in CLL patients.

Related Concept Videos

Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
892
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
2.9K
Pneumonia IV: Management01:28

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
815
Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
3.5K
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
861
Chronic Pharyngitis01:23

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
11.9K