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Study of Pituitary Morphometry Using MRI in Indian Subjects
Arun K C Singh1, Devasenathipathy Kandasamy2, Ajay Garg3
1Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India.
Indian Journal of Endocrinology and Metabolism
|October 9, 2018
Summary
This study establishes normative pituitary gland measurements for the Indian population. Females generally have larger pituitary glands than males, with distinct growth patterns observed across age groups.
Area of Science:
- Endocrinology
- Radiology
- Human Anatomy
Background:
- Accurate pituitary gland measurements are crucial for diagnosing various endocrine and neurological conditions.
- Existing normative data may not fully represent diverse populations like the Indian subcontinent.
Purpose of the Study:
- To establish normative reference ranges for pituitary gland dimensions in the Indian population.
- To investigate potential sex and age-related differences in pituitary gland size.
Main Methods:
- A cross-sectional study involving 482 Indian subjects with normal pituitary function.
- Magnetic resonance imaging (MRI) using T1-weighted images (T1-WI) for dimensional measurements.
- Calculation of pituitary gland volume from MRI data.
Main Results:
- Mean pituitary gland height, length, and volume were significantly higher in females than males overall.
- Pituitary gland width showed no significant sex-based difference.
- Age-specific analysis revealed differences in peak height timing between sexes.
Conclusions:
- The study provides essential age- and sex-specific normative data for pituitary gland measurements in Indians.
- These findings can aid in more accurate clinical assessments and diagnosis within this population.
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