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Published on: February 8, 2022
New sternal closure methods versus the standard closure method: systematic review and meta-analysis
Daniele C Cataneo1, Tarcisio A Dos Reis2, Gilmar Felisberto3
1Division of Thoracic Surgery, Department of Surgery, Botucatu School of Medicine, São Paulo State University, UNESP, São Paulo, Brazil.
New sternal closure methods show minimal difference in preventing sternal wound complications compared to standard methods. However, these novel techniques may reduce postoperative pain after sternotomy.
Area of Science:
- Cardiovascular Surgery
- Surgical Innovation
- Wound Healing Research
Background:
- Sternotomy is a common surgical approach, often leading to sternal wound complications.
- Standard sternal closure methods have been used for decades, with varying success rates in preventing complications.
- Newer sternal closure techniques aim to improve patient outcomes and reduce the incidence of sternal dehiscence and infection.
Purpose of the Study:
- To systematically review the efficiency of novel sternal closure methods in preventing sternal wound complications post-sternotomy.
- To compare the effectiveness of rigid plates, thermoreactive clips, cables, and flat wires against standard sternal closure.
- To evaluate the impact of new closure methods on deep sternal wound infection, superficial wound infection, and mortality.
Main Methods:
- Systematic review of randomized clinical trials.
- Inclusion of studies comparing new sternal closure devices (rigid plates, thermoreactive clips, cables, flat wires) with standard closure.
- Analysis of data from 1810 adult patients across seven clinical trials.
Main Results:
- New sternal closure methods demonstrated no significant difference in preventing deep sternal wound infection (RR 0.38, 95% CI 0.02-7.63) or superficial wound infection (RR 1.34, 95% CI 0.46-3.92).
- Mortality rates were similar between new and standard closure methods (RR 1.16, 95% CI 0.42-3.21).
- A statistically significant reduction in postoperative pain scores was observed with new sternal closure methods (MD -0.57, 95% CI -0.98 to -0.16).
Conclusions:
- Novel sternal closure techniques offer comparable efficacy to standard methods in preventing major sternal wound complications.
- The primary advantage of new sternal closure methods appears to be a reduction in patient-reported pain.
- Further research is needed to analyze outcomes like sternal union and hospital stay due to high heterogeneity in existing studies.
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