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[CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND ANEMIA: CLINICAL MANIFESTATIONS AND THERAPEUTIC STRATEGY].
Klinicheskaia Meditsina
|October 9, 2018
Summary
Anemia is common in COPD, particularly iron deficiency anemia in women. Treatment with erythropoietin and iron improves patient outcomes and reduces disease severity.
Area of Science:
- Pulmonary Medicine
- Hematology
Background:
- Anemia is a systemic inflammation manifestation in chronic obstructive pulmonary disease (COPD), aggravating the disease.
- Anemia affects COPD patients, with higher prevalence and severity observed in women.
Purpose of the Study:
- To investigate gender-specific characteristics of anemia in COPD patients.
- To enhance COPD treatment effectiveness using erythropoietin and enteral iron.
Main Methods:
- Clinical data from 74 patients with stage II/III COPD and anemia were analyzed.
- Treatment outcomes for 49 patients receiving standard therapy plus epoetin and Sorbiferdurules were evaluated.
Main Results:
- Iron deficiency anemia (IDA) was prevalent (85.1%), predominantly in women (61.9%).
- Anemia of chronic disease was observed in 14.9% of patients.
- IDA severity varied by gender, with moderate anemia more common in women and mild anemia in men.
Conclusions:
- Anemia prevalence in COPD is 26.5%, higher in women (33.7%) than men (20.7%).
- Anemia exacerbates COPD symptoms, especially in women, leading to increased hospitalizations.
- Erythropoietin and iron therapy improve physical endurance, reduce respiratory symptoms, and enhance tolerance in COPD patients.
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