Quality of recovery after surgery for cancer treatment

Assessment of quality of recovery is important as an end-point for outcome research. This study aims to determine the incidence and determinants of poor quality of recovery (PQR) after surgery in patients scheduled for curative neoplastic surgery.

An observational prospective study was performed in consecutive patients undergoing surgery for cancer treatment. The Quality of Recovery 15 score (QoR-15) was applied on the day before surgery (T0) and 24h after (T1). PQR was defined for patients with a QoR-15 score lower than the mean QoR-15 score at T1 minus one standard deviation. Preoperative quality of life was assessed with EuroQol-5D. Frailty and disability were defined using Clinical Frailty Scale and World Health Organization Disability Assessment Schedule 2.0.

One hundred and thirty-eight patients were enrolled and 31 (15.9%) were identified as having PQR. At T0, patients with PQR presented lower scores on total QoR-15 (P=.03) and had more problems on EuroQol-5D in mobility (P=.014), self-care (P=.027) and usual activities domains (P=.019). The difference of QoR-15 score between T1 and T0 was higher in PQR patients (P<.001). PQR had more frequently Revised Cardiac Risk Index (RCRI)≥2 (P=.012) and were more frequently frail (P=.03). PQR patients stayed longer in the hospital (P=.034).

PQR patients had lower QoR-15 before surgery, poor quality of life, were more frequently frail and had high cardiac risk factors. PQR patients stayed longer in the hospital.