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In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Modeling the burden of cardiovascular disease in Turkey
Yücel Balbay, Isabelle Gagnon-Arpin1, Simten Malhan
1The Conference Board of Canada; Ottawa, Ontario-Canada. gagnonarpin@conferenceboard.ca.
Objective:
This study aims to estimate the current and future burden of cardiovascular diseases (CVD) in Turkey.
Methods:
A burden-of-disease model was developed that included inputs on population growth, prevalence, and incidence of ischemic disease (IHD) and cerebrovascular disease (CeVD), prevalence of modifiable risk factors, mortality rates, and relationship between risk factors and IHD/CeVD. Direct costs to the public health-care system and indirect costs from lost production due to premature mortality, hospitalizations, disability, and absenteeism were considered.
Results:
We estimated that in 2016, 3.4 million Turkish adults were living with CVD, including 2.5 million affected by IHD, and 0.9 million by CeVD. This prevalence is projected to increase to 5.4 million by 2035. The economic burden of CVD was estimated at US$10.2 billion in 2016, projected to increase twofold to US$19.4 billion by 2035.
Conclusion:
Our study confirms that the current burden of CVD is significant, and that it is projected to increase at a steep rate over the next two decades. This growing burden of disease will likely create significant pressure on the public health-care system in the form of direct health-care costs, as well as on society in the form of lost productivity.
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