Related Experiment Video
Updated: Feb 4, 2026

Enumeration of Major Peripheral Blood Leukocyte Populations for Multicenter Clinical Trials Using a Whole Blood Phenotyping Assay
Published on: September 16, 2012
Achieving high HPV vaccine completion rates in a pediatric clinic population
Abbey B Berenson1, Richard Rupp1, Erin E Dinehart1,2
1a Obstetrics & Gynecology, University of Texas Medical Branch , Galveston , TX , USA.
Insights
Patient navigators significantly boosted human papillomavirus (HPV) vaccination completion rates in Texas pediatric clinics. This intervention educated families and provided reminders, overcoming barriers to HPV immunization.
Area of Science:
- Public Health
- Vaccinology
- Health Services Research
Background:
- Low human papillomavirus (HPV) vaccination rates remain a public health concern.
- Pediatric clinics face challenges in ensuring timely HPV vaccine series completion.
- Patient navigation interventions show promise in improving immunization uptake.
Purpose of the Study:
- To assess the effectiveness of patient navigators (PNs) in educating families about HPV vaccination.
- To evaluate the impact of PNs on HPV vaccine series completion through personalized reminders.
- To identify barriers and facilitators to HPV vaccination in a clinical setting.
Main Methods:
- A prospective study involving 3 pediatric clinics in Texas.
- Patient navigators (PNs) educated families and provided follow-up reminders for HPV vaccination.
- Analysis of vaccination completion rates, demographic correlates, and missed appointments.
- Qualitative interviews with 21 healthcare providers and PNs.
Main Results:
- 930 unvaccinated adolescents initiated the HPV vaccine series after PN counseling (66.9% uptake).
- 93% of HPV vaccine initiators completed the series; 85% of prior starters completed.
- Older adolescents (15-17 years) were less likely to complete the series compared to younger children.
- Providers perceived the PN program as effective in addressing vaccination barriers.
Conclusions:
- Patient navigators significantly improved HPV vaccine series completion in a pediatric setting.
- This intervention successfully addressed identified barriers to HPV vaccination.
- PNs represent a viable strategy to enhance HPV immunization rates nationally.
Abstract:
Objective: To evaluate the efficacy of an intervention utilizing patient navigators (PNs) to 1) educate families on human papillomavirus (HPV) vaccination in a clinic setting and 2) provide personalized reminders for follow-up. Method: Families with 9-17 year-old children who had no record of completing the HPV vaccination series receiving primary or specialty care in 3 pediatric clinics were approached by PNs between February 1, 2015 and August 31, 2016. Demographic characteristics, visit type, preferred contact method, rates and correlates of completion, and appointments missed were analyzed. In addition, qualitative interviews of 21 providers and PNs assessed their perceptions of the program. Results: 1,391 adolescents were identified out of 2,162 patients approached as unvaccinated or partially vaccinated prior starters; among the unvaccinated, 930 received the 1st dose after being counseled by the PN (66.9%), either immediately or at a follow-up visit soon thereafter. This included 118 siblings of patients who did not have an appointment that day. Of initiators approached between 2/1/2015 and 8/31/2016, 93% (864/930) completed the series by 8/31/2017. No differences in series completion among initiators were observed by gender or race/ethnicity, but older patients (15-17 years old) were less likely to complete than 11-12 year olds. Of the 688 patients identified as prior starters, 85% completed the series through the program. Qualitative interviews demonstrated that providers felt the program addressed major barriers to HPV vaccination. Conclusion: Employing PNs dramatically increased HPV vaccine series completion among boys and girls with historically low HPV vaccination rates at pediatric clinics in Texas. Clinic providers felt this program addressed many barriers they observed prior to program implementation. This approach could markedly improve HPV vaccine series completion rates in the US.
More Related Videos
Related Concept Videos
Vaccinations
Population Growth
Conservation of Small Populations
Speciation Rates
What is Population Genetics?
Cancer Vaccines
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...

