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Related Experiment Video

Updated: Feb 4, 2026

Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products
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Antifungal stewardship: developments in the field.

Karen F Urbancic1,2,3,4, Karin Thursky1,2,3,5,6, David C M Kong2,7,8

  • 1National Centre for Infections in Cancer, Peter MacCallum Cancer Centre.

Current Opinion in Infectious Diseases
|October 10, 2018
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Summary
This summary is machine-generated.

Antifungal stewardship (AFS) programs are crucial for combating resistance and invasive fungal diseases. While bedside reviews reduce antifungal use, integrating diagnostics and drug monitoring requires further study for patient outcome assessment.

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Area of Science:

  • Infectious Diseases
  • Antimicrobial Resistance
  • Clinical Pharmacy

Background:

  • Rising antifungal resistance and invasive fungal infections necessitate effective antifungal stewardship (AFS).
  • Despite the urgency, formal AFS programs are not widely implemented in hospitals.
  • Existing AFS programs primarily focus on bedside reviews, demonstrating reductions in antifungal consumption and costs.

Purpose of the Study:

  • To review the key drivers and components of antifungal stewardship programs.
  • To examine the evidence supporting specific AFS interventions.
  • To explore methods for assessing the performance of AFS programs.

Main Methods:

  • Literature review of antifungal stewardship programs and interventions.
  • Analysis of current practices and evidence for AFS components.
  • Examination of methods used to evaluate AFS program effectiveness.

Main Results:

  • AFS programs centered on bedside reviews have proven effective in reducing antifungal use and costs.
  • Incorporating fungal diagnostics and therapeutic drug monitoring into AFS is recommended but lacks adequate impact assessment.
  • Standardized methods for evaluating AFS program effectiveness and impact on patient outcomes are still lacking.

Conclusions:

  • The adoption of formal AFS programs has been slow, highlighting a need for new initiatives.
  • Further research is required to assess the impact of integrated AFS tools on patient outcomes.
  • Developing consensus definitions for core AFS metrics is essential for benchmarking, resourcing, and ensuring program sustainability.