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BlasterJS: A novel interactive JavaScript visualisation component for BLAST alignment results.

Aitor Blanco-Míguez1,2,3, Florentino Fdez-Riverola1,2,4, Borja Sánchez2

  • 1ESEI - Department of Computer Science, University of Vigo, Ourense, Spain.

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This new JavaScript library, BlasterJS, offers a lightweight solution for visualizing Basic Local Alignment Search Tool (BLAST) outputs in web applications. It provides interactive sequence similarity results independently of BLAST services.

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Area of Science:

  • Bioinformatics
  • Computational Biology
  • Molecular Biology

Background:

  • Basic Local Alignment Search Tool (BLAST) is a widely used tool in molecular biology.
  • There is a growing need to integrate BLAST services into larger web applications.

Purpose of the Study:

  • Introduce BlasterJS viewer, a JavaScript library for developing web applications.
  • Enable lightweight visualization of BLAST outputs.
  • Facilitate seamless integration of visual and interactive representations of BLAST results.

Main Methods:

  • Developed a new JavaScript library named BlasterJS.
  • Ensured compatibility with text outputs from various BLAST programs (BLASTp, BLASTn, BLASTx, tBLASTn, tBLASTx).
  • Designed BlasterJS to be independent of specific BLAST services.

Main Results:

  • BlasterJS focuses on visual and interactive display of sequence similarity results.
  • The library is compatible with all major web browsers.
  • BlasterJS is available via the EBI's BioJS registry, enhancing its applicability.

Conclusions:

  • BlasterJS simplifies the integration of visual and interactive BLAST output representations into web applications.
  • The library supports sequence similarity searches.
  • BlasterJS is freely accessible for use in bioinformatics applications.