Association between fine particulate matter and oral cancer among Taiwanese men

Yu-Hua Chu1,2,3, Syuan-Wei Kao4, Disline Manli Tantoh4

  • 1Department of Healthcare Administration, Asia University, Taichung City, Taiwan.

Insights

Exposure to fine particulate matter 2.5 (PM2.5) is linked to increased oral cancer risk in Taiwanese men. Higher PM2.5 concentrations correlated with a greater likelihood of developing oral cancer.

Area of Science:

  • Environmental Health
  • Oncology
  • Epidemiology

Background:

  • Air pollution, specifically fine particulate matter 2.5 (PM2.5), is a growing global health concern.
  • Previous research suggests links between air pollutants and various cancers, but specific associations with oral cancer require further investigation.

Purpose of the Study:

  • To investigate the association between exposure to fine particulate matter 2.5 (PM2.5) and the risk of oral cancer among Taiwanese men.
  • To quantify the risk of oral cancer associated with different levels of PM2.5 exposure.

Main Methods:

  • Utilized linked data from the Taiwan Cancer Registry, Adult Preventive Medical Services Database, National Health Insurance Research Database, and Air Quality Monitoring Database.
  • Included 482,659 Taiwanese men aged 40+ years, assessing PM2.5 concentrations in 2009.
  • Employed logistic regression to analyze the association between PM2.5 levels and oral cancer diagnoses from 2012-2013, adjusting for confounders.

Main Results:

  • An increased risk of oral cancer was observed in men exposed to higher concentrations of PM2.5.
  • Specifically, an odds ratio (OR) of 1.43 (95% CI 1.17 to 1.74) was found for PM2.5 concentrations ≥40.37 µg/m³ compared to the lowest quartile (<26.74 µg/m³).

Conclusions:

  • Higher exposure to fine particulate matter 2.5 (PM2.5) is associated with an elevated risk of oral cancer in Taiwanese men.
  • These findings highlight the potential impact of air quality on oral cancer incidence and underscore the need for pollution control measures.

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