[Systematic analysis of pathological changes in inflammatory dermatoses : New dermatopathological criteria and...

Standardized analysis of histological findings in a routinely stained section without knowledge of the clinical picture ("blind fashion") allows an objective assessment of the pathological changes. In inflammatory dermatoses diagnostic algorithms and criteria have been proven. They follow defined main inflammatory patterns, the composition of the inflammatory infiltrate and additional criteria. Taking into account the stage of development and the possibility of collision phenomena, this approach will give a histological diagnosis, or at least a limited number of differential diagnoses. However, the final diagnosis always results from the synopsis of the clinical picture and additional parameters. The modern development of algorithms and new histological criteria are outlined in autoimmune dermatoses, autoinflammatory syndromes, drug reactions and genodermatoses.