Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Hemodialysis II: Procedure and Complications

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...

Pneumonia III: Complications and Assessment

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:

Diabetes: Symptoms, Diagnosis, and Complications

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...

Asthma-III: Symptoms and Complications

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma

Ribosome Profiling

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The Impact of Patient Adherence to Dual Antiplatelet Medication Following Percutaneous Coronary Intervention on the Occurrence of Adverse Cardiovascular Events.

Patient preference and adherence·2024

Same author

[Reference values of platelet aggregometry in healthy subjects.]

Klinicheskaia laboratornaia diagnostika·2019

Same author

Kardiologiia·2019

Same author

[FINANCIAL AND LEGAL GUARANTEEING OF MEDICAL INSURANCE IN UKRAINE].

Georgian medical news·2019

Same author

WITHDRAWN: Author's Reply.

Journal of minimally invasive gynecology·2018

Same author

Diagnostic and therapeutic strategies for resistant arterial hypertension--focus on countries with emerging economies.

Bratislavske lekarske listy·2014

Search research articles

Related Experiment Video

Updated: Feb 4, 2026

Acute Myocardial Infarction in Rats

Acute Myocardial Infarction in Rats

Published on: February 16, 2011

[CYTOKINE PROFILE IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION WITH AND WITHOUT COMPLICATIONS].

A O Aimagambetova, L K Karazhanova, A Kotlyar

Klinicheskaia Meditsina

|October 11, 2018

Summary

This summary is machine-generated.

Elevated levels of certain cytokines, including IL-6, IL-10, and TNFα, can predict future cardiovascular complications in ST-segment elevation myocardial infarction (STEMI) patients. These markers help identify high-risk individuals for proactive management.

More Related Videos

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

Published on: October 14, 2016

Related Experiment Videos

Last Updated: Feb 4, 2026

Acute Myocardial Infarction in Rats

Acute Myocardial Infarction in Rats

Published on: February 16, 2011

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

Published on: October 14, 2016

Area of Science:

Cardiology
Immunology
Biochemistry

Background:

ST-segment elevation myocardial infarction (STEMI) is a critical cardiovascular event.
Understanding prognostic markers is crucial for patient management and risk stratification.
Cytokine profiles are increasingly recognized for their role in inflammatory processes post-MI.

Purpose of the Study:

To investigate the prognostic significance of specific cytokines in patients with STEMI.
To determine if cytokine levels can predict cardiovascular complications within one year of STEMI.
To evaluate the role of IL-6, IL-1β, IL-10, TNFα, and CRP in STEMI prognosis.

Main Methods:

Assessed cytokine (IL-6, IL-1β, IL-10, TNFα) and C-reactive protein (CRP) levels in 81 STEMI patients.
Compared cytokine concentrations between patients with complicated and uncomplicated STEMI courses.
Compared STEMI patient groups with a control group of healthy subjects.
Monitored patients for cardiovascular complications within one year post-STEMI.

Main Results:

Patients with complicated STEMI showed significantly higher concentrations of IL-6, IL-10, TNFα, and CRP on days 1, 7, and 14 compared to controls and uncomplicated STEMI patients.
Specific elevated thresholds for TNFα (>35.49 pg/ml), IL-6 (>33.37 pg/ml), IL-10 (>34 pg/ml), and CRP (>10.84 mg/l) on day 1 were associated with increased cardiovascular complications within one year.
No reliable prognostic levels for IL-1β were identified as its concentration remained within the normal range.

Conclusions:

Initial elevations in blood CRP, TNFα, IL-6, and IL-10 levels are valuable indicators for identifying STEMI patients at high risk of cardiovascular events.
These cytokine markers can aid in stratifying STEMI patients for closer monitoring and tailored therapeutic strategies.
The study highlights the prognostic utility of specific inflammatory markers in the early phase of STEMI.