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Tuberculous peritonitis following intestinal perforation in malignancy
Jiyoung Hwang1, Seong Sook Hong1, Hyun-Joo Kim1
1Department of Radiology, Soonchunhyang University College of Medicine, Seoul Hospital, Seoul, Republic of Korea.
Abstract:
Tuberculous peritonitis is one of the most common causes of exudative ascites, especially in the young, and is an important cause of extra-pulmonary disease. However, tuberculous peritonitis is challenging to diagnose because there are no pathognomonic clinical features or imaging findings. Therefore, it is commonly misdiagnosed as another type of peritoneal disease, especially so in elderly patients with malignant disease. In this report, we described two cases of tuberculous peritonitis that were observed after intestinal perforation in elderly patients with malignancies. These diagnoses were established by laparoscopic peritoneal biopsy or AFB cultures of the ascitic fluid. Both patients were treated with anti-TB medications.
Insights
Tuberculous peritonitis, a common cause of ascites, is difficult to diagnose and often mistaken for malignancy, especially in the elderly. Early diagnosis and anti-TB treatment are crucial for managing this extra-pulmonary tuberculosis.
Area of Science:
- Gastroenterology and Hepatology
- Infectious Diseases
- Oncology
Background:
- Tuberculous peritonitis is a frequent cause of exudative ascites, particularly in younger individuals.
- It represents a significant form of extrapulmonary tuberculosis.
- Diagnosis is challenging due to a lack of specific clinical or imaging features, often leading to misdiagnosis, especially in elderly patients with concurrent malignancies.
Observation:
- This report details two cases of tuberculous peritonitis in elderly patients with existing malignancies, occurring post-intestinal perforation.
- The diagnosis was confirmed through laparoscopic peritoneal biopsy and Acid-Fast Bacilli (AFB) cultures of ascitic fluid.
Findings:
- Laparoscopic biopsy and AFB cultures are effective diagnostic methods for tuberculous peritonitis.
- Prompt initiation of anti-tuberculosis (anti-TB) medication is the standard treatment.
Implications:
- Highlights the importance of considering tuberculous peritonitis in elderly patients with ascites, especially those with malignancies and a history of intestinal perforation.
- Emphasizes the need for advanced diagnostic techniques like laparoscopy and microbiological cultures when standard methods are inconclusive.
- Underscores the treatability of tuberculous peritonitis with appropriate anti-TB therapy, even in complex cases.
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