Related Experiment Video
Updated: Feb 4, 2026

Classical Short-Delay Eyeblink Conditioning in One-Year-Old Children
Published on: September 1, 2018
Relationship of fibroblast growth factor 21, sirtuin 1, visfatin, and regulators in children with short stature
Davut Sinan Kaplan1, Asuman Canak1, Emregul Isık2
1a Medical Faculty, Department of Physiology, Health Sciences Institution , University of Gaziantep , Gaziantep , Turkey.
Abstract:
Fibroblast growth factor 21 (FGF21) is mainly secreted by the liver. It is a factor that is not fully understood in relation to growth. Sirtuin 1 (SIRT1) is a deacetylase protein. It is thought that may have an effect on the release and function of GH and IGF-1. Visfatin is synthesized from adipose tissue as primary. It may be prognostic marker associated with growth factors. As a result of our work, FGF21 is not associated with short stature but levels of SIRT1 and visfatin are associated with short stature. The decrease in visfatin value in the short-stature group is thought to be due to an insufficient amount of adipose tissue, which is important for growth and development. SIRT1 might decrease GH effect by increasing STAT5 deacetylation in the liver and we think that the result of this reduction of SIRT1 would negatively impact IGF-1 and IGFBP-3 production.
More Related Videos
12:36A Human Corneal Organ Culture Model of Descemet's Stripping Only with Accelerated Healing Stimulated by Engineered Fibroblast Growth Factor 1
Published on: July 22, 2022
06:35A Mouse Model to Investigate the Role of Cancer-Associated Fibroblasts in Tumor Growth
Published on: December 22, 2020
Related Concept Videos
Relationship Growth
Role of Hematopoietic Growth Factors
Thrombopoietin (TPO), mainly released by the liver,...
Factors Influencing Microbial Growth: pH
Relationship Formation
Factors Influencing Microbial Growth: Temperature
Factors Influencing Microbial Growth: Osmolarity