Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aging01:26

Aging

703
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
703
System of Memory01:23

System of Memory

7.4K
Memory is categorized into three major systems: sensory memory, short-term memory (STM), and long-term memory (LTM). These systems differ in their capacity and the duration for which they can hold information. Sensory memory captures raw sensory input from the environment, holding it for just a few seconds or less. For example, on hearing a brief, loud sound, like a car horn honking, the sound seems to linger in the mind for a moment even after it stops. This is an instance of sensory memory...
7.4K
Working Memory01:24

Working Memory

883
Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this...
883
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

3.5K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
3.5K
Long-Term Memory01:18

Long-Term Memory

681
Long-term memory is a relatively permanent type of memory, capable of storing vast amounts of information over extended periods. Its storage capacity is generally considered unlimited.
Long-term memory can be categorized into two primary types: explicit and implicit memory. Explicit memory, also known as declarative memory, involves the conscious recollection of information that we deliberately try to remember, recall, and articulate. This type of memory encompasses specific facts, events, and...
681
Traumatic Memory01:20

Traumatic Memory

583
Emotionally traumatic events often lead to memories that are exceptionally vivid and enduring, sometimes persisting with remarkable clarity throughout an individual's life. A classic example of this phenomenon is a person who survives a car accident. Even years later, they may recall every detail of the event with startling accuracy — the screeching of the tires, the jarring impact, and the acrid smell of burning rubber. Such vividness contrasts sharply with how an individual...
583

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Demasculinized digit ratios in a sample of boys with childhood autism.

Hormones and behavior·2026
Same author

Multicenter comparison of LC-MS/MS, radioimmunoassay, and ELISA for assessment of salivary progesterone and estradiol.

Psychoneuroendocrinology·2026
Same author

P-Rex1 limits the agonist-induced internalization of GPCRs independently of its Rac-GEF activity.

Cell reports·2025
Same author

Cognitive and brain health in women with early bilateral salpingo-oophorectomy: Implications for risk, resilience, and subjective cognitive decline.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Do combined oral contraceptives have long-term effects? Little evidence of an enduring effect on cognitive function in former users.

Hormones and behavior·2025
Same author

Asymmetric thiol-modified hybrid polyoxometalates: building blocks for hierarchical nanostructured redox materials.

Nanoscale·2025

Related Experiment Video

Updated: Feb 4, 2026

A Real-world What-Where-When Memory Test
09:13

A Real-world What-Where-When Memory Test

Published on: May 16, 2017

12.1K

Estrogens, Aging, and Working Memory.

Elizabeth Hampson1

  • 1Department of Psychology, Social Sciences Center, and Department of Psychiatry, University of Western Ontario, London, ON, N6A 5C2, Canada. ehampson@uwo.ca.

Current Psychiatry Reports
|October 12, 2018
PubMed
Summary
This summary is machine-generated.

Estrogen levels may improve working memory (WM) in postmenopausal women, particularly for demanding tasks. Research suggests these effects are linked to the frontal cortex and impact cognitive aging in women.

Keywords:
EstradiolEstrogenFrontal cortexMenopauseShort-term memoryWorking memory

More Related Videos

Profiling of Estrogen-regulated MicroRNAs in Breast Cancer Cells
16:24

Profiling of Estrogen-regulated MicroRNAs in Breast Cancer Cells

Published on: February 21, 2014

20.7K
Detecting Estrogenic Ligands in Personal Care Products using a Yeast Estrogen Screen Optimized for the Undergraduate Teaching Laboratory
14:13

Detecting Estrogenic Ligands in Personal Care Products using a Yeast Estrogen Screen Optimized for the Undergraduate Teaching Laboratory

Published on: January 1, 2018

13.8K

Related Experiment Videos

Last Updated: Feb 4, 2026

A Real-world What-Where-When Memory Test
09:13

A Real-world What-Where-When Memory Test

Published on: May 16, 2017

12.1K
Profiling of Estrogen-regulated MicroRNAs in Breast Cancer Cells
16:24

Profiling of Estrogen-regulated MicroRNAs in Breast Cancer Cells

Published on: February 21, 2014

20.7K
Detecting Estrogenic Ligands in Personal Care Products using a Yeast Estrogen Screen Optimized for the Undergraduate Teaching Laboratory
14:13

Detecting Estrogenic Ligands in Personal Care Products using a Yeast Estrogen Screen Optimized for the Undergraduate Teaching Laboratory

Published on: January 1, 2018

13.8K

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Endocrinology

Background:

  • Working memory (WM) is crucial for complex cognitive tasks.
  • WM function significantly declines with age.
  • Estrogen's role in modulating WM is an area of active research.

Purpose of the Study:

  • To review recent evidence on how circulating estrogens modulate working memory function in women.
  • To explore the relationship between estrogen concentrations and WM performance in postmenopausal women.

Main Methods:

  • Review of experimental studies in rhesus monkeys.
  • Analysis of human neuroimaging studies.
  • Investigation of neurochemical and cellular mechanisms.

Main Results:

  • Increased estrogen concentrations correlate with improved WM function in postmenopausal women.
  • Enhanced WM performance is observed on tasks with high cognitive load or manipulation demands.
  • Studies indicate a prefrontal cortex locus for estrogen's effects on WM.
  • Frontal executive elements of WM are influenced by circulating estrogen levels in a region-specific manner.

Conclusions:

  • Circulating estrogen concentrations influence frontal executive elements of the working memory system.
  • These findings have significant implications for women's brain health and cognitive aging.
  • Further research is needed to define the precise neurochemical and cellular mechanisms involved.