Perforated vs. nonperforated acute appendicitis: evaluation of short-term surgical outcomes in an elderly population
Fabio Rondelli1,2, Michele De Rosa3, Paolo Stella1
1Department of General Surgery, "San Giovanni Battista" Hospital, USL Umbria 2, Foligno, Perugia, Italy.
Insights
Appendectomy outcomes in elderly patients show perforated appendicitis requires longer operative time but does not increase hospital stay or complications compared to non-perforated appendicitis.
Area of Science:
- Geriatric Surgery
- Abdominal Surgery
- Surgical Outcomes Research
Background:
- Acute appendicitis incidence is rising in the elderly, posing higher perforation risks.
- Appendectomy is a common procedure for acute appendicitis.
- Elderly patients with appendicitis face increased risks of perforation and complications.
Purpose of the Study:
- To evaluate surgical outcomes of appendectomy in elderly patients.
- To compare outcomes between perforated and non-perforated appendicitis in patients over 60.
- To analyze operative time, hospital stay, and postoperative complications.
Main Methods:
- Retrospective review of 48 patients over 60 with acute appendicitis (2011-2016).
- Patients categorized into perforated appendicitis (PA) and non-perforated appendicitis (NPA) groups.
- Comparison of demographic data, operative time, hospital stay, and complications.
Main Results:
- Perforated appendicitis (PA) group (10 patients) had a longer mean operative time (58 min) than the non-perforated appendicitis (NPA) group (43.3 min) (P=0.0013).
- Mean hospital stay was similar: 6.5 days (PA) vs. 5.4 days (NPA) (P=0.093).
- Postoperative complication rates were comparable: 30% (PA) vs. 26% (NPA) (P=0.2488). No deaths or abscesses occurred.
Conclusions:
- Perforated appendicitis in the elderly requires longer operative time but does not lead to increased hospital stay or postoperative complications compared to non-perforated appendicitis.
- Non-operative management may be considered for uncomplicated appendicitis in frail elderly patients.
- Appendectomy remains the standard surgical care for appendicitis across all age groups.
Background:
Acute appendicitis is a common acute surgical abdominal condition and despite the majority of cases are observed in children and young adults, its occurrence in the elderly seems to be increasing, with a higher risk of perforation. The aim of this study was to evaluate the surgical outcomes following appendectomy for acute appendicitis in the elderly, making a comparison between perforated and nonperforated groups regarding operative time, hospital stay and postoperative complications.
Methods:
The medical records of 48 patients over the age of 60 years who had a pathologically confirmed diagnosis of acute appendicitis from January 2011 to December 2016 were retrospectively reviewed. Patients were grouped into those with perforated and those with non-perforated appendicitis (NPA) and a comparison was made between both groups regarding demography, operative time, length of hospital stay and postoperative complications.
Results:
From 48 patients over 60 years diagnosed with acute appendicitis, a PA was removed from 10 patients (20.8%). The PA group consisted of 3 males and 7 females, and their mean age was 71.6 years (range 65-84). The NPA group included 22 males and 16 females, and their mean age was 76.5 years (range 63-96). The mean operative time was 58±18.7 minutes and 43.3±9.9 minutes in the perforated and nonperforated groups respectively, with statistically significant difference (P=0.0013). The mean length of hospital stay was similar in the PA group and in the NPA group, being 6.5±1.8 days and 5.4±1.8 days respectively, but these differences were not statistically significant (P=0.093). The frequency of postoperative complications was similar in both groups as they were observed in 3 patients (30%) of the PA group and 10 patients (26%) of the NPA group (P=0.2488). No postoperative intraabdominal abscess was observed in both groups and there was no death after the surgery.
Conclusions:
PA, despite requiring a longer mean operative time, in our series is not producing a longer hospital stay or more postoperative complications compared to NPA. The non-operative management of uncomplicated appendicitis is a reasonable option in frail patients in order to avoid the burden of morbidity related to operation, nevertheless surgery remains the standard of care in all age groups.
More Related Videos
Related Concept Videos
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Esophageal Perforation-I: Introduction
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
Conservation of Small Populations
What is Population Genetics?
Population Growth


