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Updated: Feb 4, 2026

Assessment of Physical Activity Intensity with Accelerometers and Oxygen Consumption
Published on: June 20, 2025
Physical activity for brain health in older adults
Teresa Liu-Ambrose1,2, Cindy K Barha1,2, John R Best1,2
1a Department of Physical Therapy, Aging, Mobility, and Cognitive Neuroscience Laboratory, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Abstract:
Physical activity is a promising strategy for dementia prevention and disease modification. Here, we provide a narrative review of the current evidence from epidemiological and intervention studies on the role of physical activity and exercise in promoting cognitive health in older adults both without and with cognitive impairment. We highlight some of the potential underlying mechanisms and discuss biological sex as a potential moderating factor. We conclude with limitations and future directions for this rapidly expanding line of research.
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